Analytical Data
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Gene name
SNX7
- Application
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Alternative Names
anti-MGC8717; DKFZP564F052; MGC8717; MGC8717; SNX7; SNX7_HUMAN; Sorting nexin 7; Sorting nexin 7 isoform a; Sorting nexin-7
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UNH6
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Expression Region
1-387 aa
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AA Sequence
MDMNSFSPMM PTSPLSMINQ IKFEDEPDLK DLFITVDEPE SHVTTIETFI TYRIITKTSR GEFDSSEFEV RRRYQDFLWL KGKLEEAHPT LIIPPLPEKF IVKGMVERFN DDFIETRRKA LHKFLNRIAD HPTLTFNEDF KIFLTAQAWE LSSHKKQGPG LLSRMGQTVR AVASSMRGVK NRPEEFMEMN NFIELFSQKI NLIDKISQRI YKEEREYFDE MKEYGPIHIL WSASEEDLVD TLKDVASCID RCCKATEKRM SGLSEALLPV VHEYVLYSEM LMGVMKRRDQ IQAELDSKVE VLTYKKADTD LLPEEIGKLE DKVECANNAL KADWERWKQN MQNDIKLAFT DMAEENIHYY EQCLATWESF LTSQTNLHLE EASEDKP
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Molecular Weight
45.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SNX7 (Sorting Nexin 7) is a member of the sorting nexin family, which plays a crucial role in endosomal trafficking and the regulation of membrane protein localization. The protein is known for its involvement in the recycling of receptors and signaling proteins, influencing pathways essential for cellular communication and homeostasis. Recent studies have indicated that SNX7 may have significant implications in various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes due to its role in modulating receptor signaling and endosomal dynamics. Understanding the structure and function of SNX7 and the mechanisms by which it regulates these processes is fundamental for elucidating its role in pathophysiology. The development of recombinant SNX7 protein allows for detailed biochemical and biophysical studies, enabling researchers to dissect its functional domains, interactions with other cellular components, and its regulatory mechanisms. This research can potentially pave the way for therapeutic interventions aimed at correcting dysregulated endosomal trafficking and receptor signaling associated with disease.
