Analytical Data
-
基因名
SNX7
- Application
-
别名
anti-MGC8717; DKFZP564F052; MGC8717; MGC8717; SNX7; SNX7_HUMAN; Sorting nexin 7; Sorting nexin 7 isoform a; Sorting nexin-7
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9UNH6
-
表达区间
1-387 aa
-
氨基酸序列
MDMNSFSPMM PTSPLSMINQ IKFEDEPDLK DLFITVDEPE SHVTTIETFI TYRIITKTSR GEFDSSEFEV RRRYQDFLWL KGKLEEAHPT LIIPPLPEKF IVKGMVERFN DDFIETRRKA LHKFLNRIAD HPTLTFNEDF KIFLTAQAWE LSSHKKQGPG LLSRMGQTVR AVASSMRGVK NRPEEFMEMN NFIELFSQKI NLIDKISQRI YKEEREYFDE MKEYGPIHIL WSASEEDLVD TLKDVASCID RCCKATEKRM SGLSEALLPV VHEYVLYSEM LMGVMKRRDQ IQAELDSKVE VLTYKKADTD LLPEEIGKLE DKVECANNAL KADWERWKQN MQNDIKLAFT DMAEENIHYY EQCLATWESF LTSQTNLHLE EASEDKP
-
分子量
45.3 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SNX7 (Sorting Nexin 7) is a member of the sorting nexin family, which plays a crucial role in endosomal trafficking and the regulation of membrane protein localization. The protein is known for its involvement in the recycling of receptors and signaling proteins, influencing pathways essential for cellular communication and homeostasis. Recent studies have indicated that SNX7 may have significant implications in various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes due to its role in modulating receptor signaling and endosomal dynamics. Understanding the structure and function of SNX7 and the mechanisms by which it regulates these processes is fundamental for elucidating its role in pathophysiology. The development of recombinant SNX7 protein allows for detailed biochemical and biophysical studies, enabling researchers to dissect its functional domains, interactions with other cellular components, and its regulatory mechanisms. This research can potentially pave the way for therapeutic interventions aimed at correcting dysregulated endosomal trafficking and receptor signaling associated with disease.
