Analytical Data
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基因名
DDX19
- Application
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别名
ATP dependent RNA helicase DDX19A; ATP-dependent RNA helicase DDX19A; DD19A_HUMAN; DDX19 like protein; DDX19-like protein; DDX19A; DDX19L; DEAD box protein 19A
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UMR2
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表达区间
1-479aa
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氨基酸序列
MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN
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分子量
78.43 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DDX19, also known as DEAD-box helicase 19, is a member of the DEAD-box RNA helicase family, playing critical roles in various cellular processes including RNA metabolism, translation initiation, and ribosome biogenesis. The significance of DDX19 in cellular function and its potential implications in cancer and viral infections have sparked research interest. It is known to facilitate the export of RNA from the nucleus to the cytoplasm, a process vital for gene expression regulation. Studies have shown that DDX19 interacts with several RNA-binding proteins and is involved in the maintenance of cellular homeostasis. Additionally, aberrations in DDX19 expression levels have been linked to the progression of multiple cancer types, making it a potential target for therapeutic intervention. The development of recombinant DDX19 protein allows for detailed investigations into its biochemical properties and interactions at the molecular level, providing insight into its functional dynamics. By studying the structure and mechanisms of DDX19 in vitro and in vivo, researchers aim to elucidate its role in disease pathogenesis and explore its potential as a biomarker or therapeutic target. Thus, recombinant DDX19 protein research not only enhances our understanding of fundamental cellular processes but also opens avenues for innovative strategies in disease management.
