Analytical Data
-
基因名
SNX27
- Application
-
别名
KIAA0488; Methamphetamine responsive transcript 1; MGC126871; MGC126873; MGC20471; MRT1; MY014; OTTHUMP00000042487; RP11-98D18.12; SNX27; SNX27_HUMAN; Sorting nexin family member 27; Sorting nexin-27
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q96L92
-
表达区间
1-541 aa
-
氨基酸序列
MADEDGEGIH PSAPHRNGGG GGGGGSGLHC AGNGGGGGGG PRVVRIVKSE SGYGFNVRGQ VSEGGQLRSI NGELYAPLQH VSAVLPGGAA DRAGVRKGDR ILEVNHVNVE GATHKQVVDL IRAGEKELIL TVLSVPPHEA DNLDPSDDSL GQSFYDYTEK QAVPISVPRY KHVEQNGEKF VVYNVYMAGR QLCSKRYREF AILHQNLKRE FANFTFPRLP GKWPFSLSEQ QLDARRRGLE EYLEKVCSIR VIGESDIMQE FLSESDENYN GVSDVELRVA LPDGTTVTVR VKKNSTTDQV YQAIAAKVGM DSTTVNYFAL FEVISHSFVR KLAPNEFPHK LYIQNYTSAV PGTCLTIRKW LFTTEEEILL NDNDLAVTYF FHQAVDDVKK GYIKAEEKSY QLQKLYEQRK MVMYLNMLRT CEGYNEIIFP HCACDSRRKG HVITAISITH FKLHACTEEG QLENQVIAFE WDEMQRWDTD EEGMAFCFEY ARGEKKPRWV KIFTPYFNYM HECFERVFCE LKWRKENIFQ MARSQQRDVA T
-
分子量
61.2 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SNX27 (Sorting Nexin 27) is a member of the sorting nexin family, which plays a critical role in the intracellular trafficking of membrane proteins. This protein is known for its involvement in the endosomal recycling pathway, particularly in the recycling of G-protein coupled receptors (GPCRs) and other membrane proteins back to the plasma membrane. Research surrounding SNX27 has gained momentum due to its potential implications in various physiological and pathological processes, including neurodegenerative diseases, cancer progression, and metabolic disorders. Recent studies have focused on understanding the molecular mechanisms by which SNX27 interacts with its binding partners and influences their cellular localization and function. Additionally, the generation of recombinant SNX27 protein has enabled researchers to dissect its structural properties, functional domains, and the precise molecular interactions it engages in. This research is crucial for identifying potential therapeutic targets, as dysregulation of SNX27 and its pathway has been linked with significant disease states. As such, the production and characterization of recombinant SNX27 not only facilitate fundamental biological studies but also pave the way for developing novel intervention strategies aimed at modulating the trafficking of membrane proteins implicated in various diseases.
