Analytical Data
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Gene name
PITPNM3
- Application
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Alternative Names
PITPNM3；NIR1；Membrane-associated phosphatidylinositol transfer Protein 3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BZ71
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Expression Region
387-597aa
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AA Sequence
LGRFDFDVSDFFLFGSPLGLVLAMRRTVLPGLDGFQVRPACSQVYSFFHCADPSASRLEPLLEPKFHLVPPVSVPRYQRFPLGDGQSLLLADALHTHSPLFLEGSSRDSPPLLDAPASPPQASRFQRPGRRMSEGSSHSESSESSDSMAPVGASRITAKWWGSKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYES
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Molecular Weight
30.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PITPNM3 (Phosphatidylinositol Transfer Protein, Membrane-associated 3) is a member of the phosphatidylinositol transfer protein family, which plays critical roles in intracellular lipid transport and signaling pathways. It is implicated in various cellular processes, including membrane trafficking, cytoskeletal dynamics, and cell signaling. Recent studies have suggested that PITPNM3 may be involved in cancer, neurodegeneration, and immune responses due to its ability to regulate phosphoinositide levels, which are essential for membrane integrity and function. The protein's distinct structure, characterized by a lipid-binding domain, allows it to interact with different lipids, thereby influencing various cellular functions. The investigation of PITPNM3's recombinant protein holds great potential for understanding its biological roles at a molecular level, providing insights into its mechanisms and interactions within the cell. Given the increasing evidence linking PITPNM3 to disease states, the production and characterization of recombinant PITPNM3 can facilitate the exploration of its therapeutic potential, making it a significant target for future research in cell biology and disease treatment.
