Analytical Data
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Gene name
PLXNA4
- Application
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Alternative Names
PLXNA4；KIAA1550；PLXNA4A；PLXNA4B；Plexin-A4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9HCM2
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Expression Region
25-521aa
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AA Sequence
LLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKSFGTGPQGGITQEWIGVEGDPPGANIASQEQMLCVYLQCSSHKAISDQRVQPLLCCFLNVPGNS
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Molecular Weight
60.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLXNA4 (Plexin A4) is a member of the plexin family of receptors, which are known to play crucial roles in axon guidance and neural development. Research into PLXNA4 has gained momentum due to its implications in various neurological conditions and its potential role in cancer biology. Specifically, it is involved in mediating signals from semaphorins, a class of proteins that regulate cellular processes such as migration, adhesion, and differentiation. Abnormal expression or mutations in PLXNA4 have been linked to neurological disorders, highlighting its significance in maintaining neural connectivity. Additionally, its expression patterns in different tissues suggest that PLXNA4 may be a key player in other biological processes beyond the nervous system. The creation of recombinant PLXNA4 proteins is essential for elucidating its functional mechanisms. By studying these proteins in vitro, researchers aim to better understand their role in signaling pathways and their interactions with other cellular molecules. This research not only sheds light on fundamental biological processes but also opens potential avenues for therapeutic interventions targeting PLXNA4-related pathways in various diseases, including neurodegenerative disorders and tumors. Overall, the investigation of PLXNA4 recombinant proteins represents a critical step in advancing our understanding of its biological functions and therapeutic potential.
