Analytical Data
-
基因名
DCUN1D2
- Application
-
别名
DCUN1D2; C13orf17; DCUN1L2DCN1-like protein 2; DCUN1 domain-containing protein 2; Defective in cullin neddylation protein 1-like protein 2
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q6PH85
-
表达区间
1-259aa
-
氨基酸序列
MHKLKSSQKDKVRQFMACTQAGERTAIYCLTQNEWRLDEATDSFFQNPDSLHRESMRNAVDKKKLERLYGRYKDPQDENKIGVDGIQQFCDDLSLDPASISVLVIAWKFRAATQCEFSRKEFLDGMTELGCDSMEKLKALLPRLEQELKDTAKFKDFYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGRFKFLDLWNTFLMEHHKRSIPRDTWNLLLDFGNMIADDMSNYDEEGAWPVLIDDFVEYARPVVTGGKRSLF
-
分子量
56.6 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Recombinant Human SNIP Protein，GST
Cat：PAX2000-11540
Recombinant Human DC-UbP Protein，GST
Cat：PA2000-7020
Protein Description
DCUN1D2 is a member of the DCUN1D family of proteins, which are known to play critical roles in cellular processes such as protein degradation, cell cycle regulation, and development. Research has indicated that DCUN1D2 may be involved in the regulation of the ubiquitin-proteasome system, which is essential for maintaining cellular homeostasis by controlling the degradation of misfolded or redundant proteins. Furthermore, mutations or dysregulation of DCUN1D2 have been associated with various diseases, including cancer and genetic disorders, making it a potential target for therapeutic intervention. Recent studies have focused on the characterization of DCUN1D2 as a recombinant protein to investigate its structural properties, binding interactions, and functional mechanisms in cellular pathways. By producing and purifying DCUN1D2 in a recombinant system, researchers aim to elucidate its role in ubiquitin ligase activity and its implications in disease. Understanding the function of DCUN1D2 not only contributes to the fundamental knowledge of protein homeostasis but also holds promise for developing targeted therapies that could mitigate the effects of its dysregulation in pathological conditions.
