Analytical Data
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Gene name
DCUN1D3
- Application
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Alternative Names
DCUN1D3; SCCRO3DCN1-like protein 3; DCUN1 domain-containing protein 3; Defective in cullin neddylation protein 1-like protein 3; Squamous cell carcinoma-related oncogene 3
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IWE4
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Expression Region
1-304aa
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AA Sequence
MGQCVTKCKNPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLPTSSGDAGRESKSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREGEGRGALSSGPEGLCPEEQT
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Molecular Weight
60.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DCUN1D3, also known as "Defective in Culler Nephropathy 1, Domain 3," is a protein that has garnered attention in the field of molecular biology and biochemistry due to its potential roles in cellular processes and disease mechanisms. Research indicates that DCUN1D3 may be involved in protein quality control and degradation pathways, particularly through its interaction with the ubiquitin-proteasome system, which is crucial for maintaining cellular homeostasis. Aberrant expression or mutations in DCUN1D3 have been implicated in various pathologies, including certain cancers and developmental disorders, highlighting its importance in health and disease. As a member of the DCUN1D protein family, studies have focused on elucidating its structure-function relationships, post-translational modifications, and interaction partners. Understanding the functional dynamics of DCUN1D3 can provide insights into its role in cellular signaling and the underlying mechanisms of disorders associated with its dysregulation. Thus, ongoing research into the recombinant expression and characterization of DCUN1D3 aims to uncover its biological significance and therapeutic potential, paving the way for innovative treatments that target related pathways.
