Analytical Data
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Gene name
DBX2
- Application
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Alternative Names
DBX2Homeobox protein DBX2; Developing brain homeobox protein 2
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6ZNG2
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Expression Region
1-339aa
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AA Sequence
MLPSAVAAHA GAYWDVVASS ALLNLPAAPG FGNLGKSFLI ENLLRVGGAP TPRLQPPAPH DPATALATAG AQLRPLPASP VPLKLCPAAE QVSPAGAPYG TRWAFQVLSP SADSARLPGR APGDRDCTFQ PSAPAPSKPF LLSTPPFYSA CCGGSCRRPA SSTAFPREES MLPLLTQDSN SKARRGILRR AVFSEDQRKA LEKMFQKQKY ISKTDRKKLA INLGLKESQV KIWFQNRRMK WRNSKEKEVL SNRCIQEVGL QEDPLSRSAL GFPSPCPSIW DVPQQHSSPR WRENSPEPSE RLIQESSGAP PPEANSLQGA LYLCSEEEAG SKGVLTGAV
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Molecular Weight
63.69 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DBX2, or Dorsal root Ganglion cells-associated homeobox protein 2, is a member of the homeobox gene family, playing a crucial role in the development of the nervous system, particularly in the differentiation and specification of neural progenitor cells. Recent studies have highlighted its significance in the formation of sensory neurons and spinal cord development. Research on DBX2 has gained momentum due to its potential implications in neurological disorders and regenerative medicine. Understanding its expression patterns and regulatory mechanisms could provide insights into neural development and the underlying causes of various neural pathologies. Moreover, DBX2’s precise involvement in signaling pathways offers opportunities for innovative therapeutic strategies targeting neurodegenerative diseases. As a recombinant protein, DBX2 can be produced and studied in vitro, facilitating investigations into its functional properties and interactions with other proteins. This research is not only vital for elucidating the developmental processes of neural tissues but also for advancing our ability to manipulate these pathways for therapeutic ends, such as in stem cell therapy or injury repair in the nervous system. Thus, the investigation of DBX2 recombination protein stands at the intersection of developmental biology, molecular genetics, and clinical applications, making it a focal point for ongoing scientific inquiry into neural health and disease.
