Cat: PA2000-7007

Recombinant Human DBX1 Protein,GST

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Analytical Data

  • Gene name

    DBX1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    DBX1Homeobox protein DBX1; Developing brain homeobox protein 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    A6NMT0

  • Expression Region

    1-382aa

  • AA Sequence

    MMFPGLLAPPAGYPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSVPTASMSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFLKFGVNAILSSGPRTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSDPQHLRDPRLPGPLPPSPAHSSSPGKPSDFSDSEEEEEGEEQEEITVS

  • Molecular Weight

    42.1 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

DBX1 (Differentiation and Migration of Neurons) is a transcription factor critical for the development of the vertebrate central nervous system, specifically in the specification and differentiation of excitatory neurons in the spinal cord and brain. It plays a significant role in neurogenesis and neural lineage specification by regulating the expression of downstream target genes. Research into DBX1 recombinant proteins aims to elucidate its functional mechanisms and potential therapeutic applications. Understanding DBX1's role in neuronal development can provide insights into neurodevelopmental disorders, such as autism spectrum disorders and spinal cord injuries. Furthermore, the production of recombinant DBX1 proteins allows for the exploration of protein interactions, signaling pathways, and the development of models that can mimic the in vivo conditions of neuronal differentiation. Such studies can contribute to regenerative medicine strategies, seeking to harness the regenerative potential of neural stem cells. Utilizing DBX1 and its recombinant forms in experimental applications could pave the way for novel interventions in neurodegenerative diseases and enhance our comprehension of neuronal plasticity and repair mechanisms in the nervous system. Overall, the investigation of DBX1 recombinant proteins stands at the intersection of developmental biology and clinical neuroscience, offering valuable tools for advancing our understanding of neural development and potential therapeutic avenues.

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