Analytical Data
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Gene name
DBX1
- Application
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Alternative Names
DBX1Homeobox protein DBX1; Developing brain homeobox protein 1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
A6NMT0
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Expression Region
1-382aa
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AA Sequence
MMFPGLLAPPAGYPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSVPTASMSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFLKFGVNAILSSGPRTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSDPQHLRDPRLPGPLPPSPAHSSSPGKPSDFSDSEEEEEGEEQEEITVS
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Molecular Weight
42.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DBX1 (Differentiation and Migration of Neurons) is a transcription factor critical for the development of the vertebrate central nervous system, specifically in the specification and differentiation of excitatory neurons in the spinal cord and brain. It plays a significant role in neurogenesis and neural lineage specification by regulating the expression of downstream target genes. Research into DBX1 recombinant proteins aims to elucidate its functional mechanisms and potential therapeutic applications. Understanding DBX1's role in neuronal development can provide insights into neurodevelopmental disorders, such as autism spectrum disorders and spinal cord injuries. Furthermore, the production of recombinant DBX1 proteins allows for the exploration of protein interactions, signaling pathways, and the development of models that can mimic the in vivo conditions of neuronal differentiation. Such studies can contribute to regenerative medicine strategies, seeking to harness the regenerative potential of neural stem cells. Utilizing DBX1 and its recombinant forms in experimental applications could pave the way for novel interventions in neurodegenerative diseases and enhance our comprehension of neuronal plasticity and repair mechanisms in the nervous system. Overall, the investigation of DBX1 recombinant proteins stands at the intersection of developmental biology and clinical neuroscience, offering valuable tools for advancing our understanding of neural development and potential therapeutic avenues.











