Analytical Data
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Gene name
TEKT5
- Application
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Alternative Names
TEKT5；Tektin-5
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96M29
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Expression Region
1-485aa
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AA Sequence
MEFLGTTQTASYCGPKKCCGLTSLPAVQAPVIQECYQPYYLPGYRYLNSWRPSLFYKIANVQTCPDESTSTLRPPTILPTLRSALFSRYSPHDWDQSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKCFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQLKLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHELAIKANTLCIDKEKCMGMRKTFPCTPRLVGHT
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Molecular Weight
72.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TEKT5, a member of the tektin family of proteins, plays a crucial role in the assembly and stabilization of the axoneme structure in cilia and flagella, which are vital for cellular motility and signaling. Research into TEKT5 has gained traction due to its potential implications in male fertility and embryonic development, as it is primarily expressed in the testes and is essential for sperm flagellum function. Previous studies have suggested that mutations or dysregulation of TEKT5 can lead to asthenozoospermia, a condition characterized by reduced sperm motility, which significantly impacts reproductive health. Additionally, TEKT5's involvement in cellular processes beyond spermatogenesis, such as its potential role in the formation and maintenance of other ciliary structures, makes it an interesting target for further investigation. Understanding the molecular mechanisms by which TEKT5 operates could provide insights into various ciliopathies and reproductive disorders, ultimately contributing to the development of therapeutic strategies for addressing male infertility. Given the increasing prevalence of such conditions, research into TEKT5 is not only scientifically important but also holds potential for social and medical advancements in reproductive health.
