Analytical Data
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Gene name
SMAP1
- Application
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Alternative Names
SMAP1; Stromal membrane-associated protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IYB5
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Expression Region
1-467 aa
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AA Sequence
MATRSCREKA QKLNEQHQLI LSKLLREEDN KYCADCEAKG PRWASWNIGV FICIRCAGIH RNLGVHISRV KSVNLDQWTA EQIQCMQDMG NTKARLLYEA NLPENFRRPQ TDQAVEFFIR DKYEKKKYYD KNAIAITNIS SSDAPLQPLV SSPSLQVD KNKLEKEKEK KKEEKKREKE PEKPAKPLTA EKLQKKDQQL EPKKSTSPKK EPTVDLLG LDGPAVAPVT NGNTTVPPLN DDLDIFGPMI SNPLPATVMP PAQGTPSAPA TLSTVTSG DLDLFTEQTT KSEEVAKKQL SKDSILSLYG TGTIQQQSTP GVFMGPTNIP FTSQAPFQ GFPSMGVPVP PGLIGNVM GQSPSMMVGM PMPNGFMGNA QTGVMPLPQN VVGPQGGMVG QMGAPQSKFG LPQAQQPQWS LSQMNQQMAG MSISSATPTA GFGQPSSTTA GWSGSSSGQT LSTQLWK
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Molecular Weight
50.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The SMAP1 (Small Membrane-Associated Protein 1) protein is a key player in various cellular processes, particularly in the context of membrane traffic and protein sorting. Initially identified in studies focused on membrane dynamics, SMAP1 has garnered attention for its unique structural features and functional roles within the endosomal-lysosomal pathway. Research has revealed that SMAP1 is involved in the regulation of vesicular transport and may play a critical role in cellular communication and homeostasis. Its reconstitution as a recombinant protein facilitates detailed investigations into its biochemical properties, interactions with other cellular components, and mechanistic pathways. Studies utilizing SMAP1 recombinant proteins have aimed to elucidate its functionality in various biological contexts, including its potential implications in diseases related to cellular transport dysfunctions, such as neurodegeneration and cancer. Moreover, understanding the molecular mechanisms governing SMAP1's interactions with other proteins and membranes holds promise for developing therapeutic strategies targeting these pathways. As researchers continue to explore the multifaceted roles of SMAP1, its study represents a significant endeavor in cell biology and molecular medicine, contributing to a broader understanding of membrane-associated proteins and their vital functions in maintaining cellular integrity and communication.
