Analytical Data
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Gene name
CUZD1
- Application
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Alternative Names
CUZD1；CUB and zona pellucida-like domain-containing Protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86UP6
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Expression Region
1-607aa
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AA Sequence
MELVRRLMPLTLLILSCLAELTMAEAEGNASCTVSLGGANMAETHKAMILQLNPSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINTTSLTCSSDRMRVIISKSYLEAFNSNGNNLQLKDPTCRPKLSNVVEFSVPLNGCGTIRKVEDQSITYTNIITFSASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYITEDDVIQSQNALGKYNTSMALFESNSFEKTILESPYYVDLNQTLFVQVSLHTSDPNLVVFLDTCRASPTSDFASPTYDLIKSGCSRDETCKVYPLFGHYGRFQFNAFKFLRSMSSVYLQCKVLICDSSDHQSRCNQGCVSRSKRDISSYKWKTDSIIGPIRLKRDRSASGNSGFQHETHAEETPNQPFNSVHLFSFMVLALNVVTVATITVRHFVNQRADYKYQKLQNY
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CUZD1, or CUB and Zona Pellucida-like domain-containing protein 1, has emerged as a significant focus of research due to its potential roles in various physiological and pathological processes, particularly in cancer biology. Originally identified as a gene associated with multiple carcinomas, CUZD1 is believed to contribute to tumor progression and metastasis. Its unique structure, characterized by CUB and zona pellucida domains, suggests functions in cell adhesion, signaling, and extracellular matrix interactions. Studies have indicated that CUZD1 expression is often upregulated in tumor tissues compared to normal tissues, raising interest in its potential as a biomarker for early cancer detection and prognosis. In addition, the protein's involvement in regulating immune responses has been suggested, linking it to tumor immunity and the tumor microenvironment. The generation of recombinant CUZD1 proteins allows researchers to investigate its specific biological functions and mechanisms of action in detail, paving the way for the development of targeted therapeutic strategies. Understanding the role of CUZD1 in cellular processes could provide critical insights into novel cancer therapies and improve patient outcomes. Given its emerging importance, ongoing studies aim to elucidate the precise molecular pathways involving CUZD1 and explore its potential applications in diagnosis and treatment, thereby underscoring its significance in both fundamental research and clinical contexts.
