Analytical Data
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基因名
SLC7A2
- Application
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别名
ATRC2; 20.5; Amino acid transporter; cationic 2 (low affinity); ATRC 2; CAT 2; CAT-2; CAT2; Cat2a; Cat2b; Cationic amino acid transporter 2A; cationic amino acid transporter; y+ system; low affinity cationic amino acid transporter 2; CTR2_HUMAN; HCAT 2; HCAT2; Low affinity cationic amino acid transporter 2; OTTHUMP00000216432; OTTHUMP00000216433; OTTMUSP00000041667; OTTMUSP00000041669; RCAT2; SLC7A 2; Slc7a2; Solute carrier family 7 member 2; T cell early activation protein; Tea
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P52569
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表达区间
1-657 aa
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氨基酸序列
MIPCRAALTFARCLIRRKIVTLDSLEDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQIGQFLRTYFRMNYTGLAEYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKRQSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLSYDQPKCSPEKDGLGSSPRVTSKSESQVTMLQRQGFSMRTLFCPSLLPTQQSASLVSFLVGFLAFLVLGLSVLTTYGVHAITRLEAWSLALLALFLVLFVAIVLTIWRQPQNQQKVAFMVPFLPFLPAFSILVNIYLMVQLSADTWVRFSIWMAIGFLIYFSYGIRHSLEGHLRDENNEEDAYPDNVHAAAEEKSAIQANDHHPRNLSSPFIFHEKTSEF
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分子量
98.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC7A2, also known as the solute carrier family 7 member 2, encodes a protein that functions as an amino acid transporter, primarily responsible for the uptake of neutral amino acids in various tissues. This protein plays a critical role in regulating amino acid homeostasis, which is essential for numerous physiological processes, including protein synthesis, neurotransmission, and metabolism. Abnormalities in SLC7A2 expression and function have been linked to several health conditions, including mental disorders, obesity, and metabolic syndromes. The study of recombinant SLC7A2 protein is vital for elucidating its structure-function relationships and understanding the molecular mechanisms underlying its transport activity. Recombinant proteins allow for the investigation of SLC7A2's substrate specificity, transport kinetics, and interaction with inhibitors or activators, which can provide insights into potential therapeutic targets for diseases associated with its dysfunction. Furthermore, advancements in recombinant protein production techniques enhance the ability to generate large quantities of SLC7A2, facilitating both in vitro and in vivo studies. This research not only contributes to the basic understanding of amino acid transport but also holds promise for the development of novel pharmacological strategies aimed at modulating SLC7A2 activity to improve health outcomes in related disorders.
