Analytical Data
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Gene name
CYLC1
- Application
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Alternative Names
CYLC1; CYL; CYL1Cylicin-1; Cylicin I; Multiple-band polypeptide I
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P35663
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Expression Region
1-651aa
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AA Sequence
MSLPRLLKVNIRTYDNSIPISESSRKSWNQKHFALTFPKPLQRGTNDKSRPLKSQITVTRHDKRKLEEGQKPAHKWIRHSFRKILQWPPIYTAAREQTPFRHLYTSKTHLKKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVPPSREKPPLPACEPSLPSPKVRRLCWCKMPPPPPKPRYAPLPEAPWIHKLL
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Molecular Weight
71.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CYLC1, or Cyclin L1, is a member of the cyclin family of proteins that play crucial roles in the regulation of the cell cycle and gene expression. Research into CYLC1 has gained significance due to its involvement in various cellular processes, including RNA splicing and transcription regulation. Abnormalities in CYLC1 expression have been linked to several diseases, including cancer, as it can influence cell proliferation and apoptosis. Additionally, CYLC1 is known to interact with other proteins to form complexes that are essential for proper cell cycle progression and mRNA processing. Understanding the structure and function of CYLC1, along with its regulatory mechanisms, could provide insights into its role in tumorigenesis and other diseases. Consequently, researchers are investigating the potential of CYLC1 as a therapeutic target and biomarker for cancer diagnosis and treatment. Advances in recombinant protein technology have enabled the production of CYLC1 in vitro, facilitating detailed studies of its biochemical properties, interactions, and functional implications in various cellular contexts. This body of research aims to elucidate the multifaceted roles of CYLC1 in cellular homeostasis and its contributions to disease pathology, ultimately paving the way for novel therapeutic strategies.
