Cat: PA2000-3310

Recombinant Human RAB3C Protein,His

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Analytical Data

  • 基因名

    RAB3C

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    RAB3C;Ras-related Protein Rab-3C

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q96E17

  • 表达区间

    1-227aa

  • 氨基酸序列

    MRHEAPMQMASAQDARYGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDERVISTERGQHLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAKQNTRLKETPPPPQPNCAC

  • 分子量

    42.0 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

RAB3C is a member of the RAB family of small GTPases, which are key regulators of intracellular vesicular trafficking, particularly in neurotransmitter release and synaptic function. It plays a crucial role in the regulation of exocytosis by modulating the movement and docking of synaptic vesicles to the plasma membrane in neurons. Research into RAB3C's function has gained momentum due to its potential implications in various neurological disorders, including schizophrenia and autism spectrum disorders. The study of RAB3C, particularly in the context of its recombinant protein form, allows researchers to dissect its molecular mechanisms and interactions with other proteins involved in synaptic transmission. By producing RAB3C as a recombinant protein, scientists can conduct detailed biochemical assays to analyze its GTPase activity, protein-protein interactions, and role in vesicle trafficking. These investigations provide insights into the fundamental processes of neurotransmission and the pathophysiology of neuropsychiatric diseases, thereby highlighting RAB3C as a promising target for therapeutic interventions in the realm of neuroscience. Understanding the intricate functions of RAB3C through recombinant protein studies may pave the way for novel approaches to modulate synaptic activity and address the underlying causes of various mental health conditions.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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