Cat: PAX2000-11455

Recombinant Human SLC44A2 Protein,GST

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Analytical Data

  • Gene name

    SLC44A2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Choline transporter like protein 2; Choline transporter-like protein 2; CTL 2; CTL2; CTL2_HUMAN; DKFZp666A071; FLJ44586; PP1292; SLC44A2; Solute carrier family 44 (choline transporter) member 2; Solute carrier family 44 member 2; Testicular tissue protein Li 47

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8IWA5

  • Expression Region

    1-706 aa

  • AA Sequence

    MGDERPHYYGKHGTPQKYDPTFKGPIYNRGCTDIICCVFLLLAIVGYVAVGIIAWTHGDPRKVIYPTDSRGEFCGQKGTKNENKPYLFYFNIVKCASPLVLLEFQCPTPQICVEKCPDRYLTYLNARSSRDFEYYKQFCVPGFKNNKGVAEVLRDGDCPAVLIPSKPLARRCFPAIHAYKGVLMVGNETTYEDGHGSRKNITDLVEGAKKANGVLEARQLAMRIFEDYTVSWYWIIIGLVIAMAMSLLFIILLRFLAGIMVWVMIIMVILVLGYGIFHCYMEYSRLRGEAGSDVSLVDLGFQTDFRVYLHLRQTWLAFMIILSILEVIIILLLIFLRKRILIAIALIKEASRAVGYVMCSLLYPLVTFFLLCLCIAYWASTAVFLSTSNEAVYKIFDDSPCPFTAKTCNPETFPSSNESRQCPNARCQFAFYGGESGYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWALRKPDDLPAFPLFSAFGRALRYHTGSLAFGALILAIVQIIRVILEYLDQRLKAAENKFAKCLMTCLKCCFWCLEKFIKFLNRNAYIMIAIYGTNFCTSARNAFFLLMRNIIRVAVLDKVTDFLFLLGKLLIVGSVGILAFFFFTHRIRIVQDTAPPLNYYWVPILTVIVGSYLIAHGFFSVYGMCVDTLFLCFLEDLERNDGSAERPYFMSSTLKKPLNKTNKKAAES

  • Molecular Weight

    106.5 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SLC44A2, a member of the solute carrier family 44, plays a crucial role in the transport of choline and related compounds across cell membranes, influencing various physiological processes, including lipid metabolism and neurotransmission. Dysregulation of SLC44A2 has been implicated in several health conditions, such as neurological disorders and cardiovascular diseases. The understanding of SLC44A2's functions has prompted researchers to investigate its potential as a therapeutic target. Recombinant SLC44A2 protein is generated for studies aimed at elucidating its transport mechanisms, substrate specificity, and interactions with other cellular components. By utilizing techniques such as gene cloning and expression in heterologous systems, scientists are able to produce large quantities of this protein for biochemical assays. The research focuses not only on the protein's structure-function relationship but also its potential to serve as a biomarker for disease states or a target for drug development. This ongoing research not only aims to clarify the biological roles of SLC44A2 but also to pave the way for innovative therapeutic strategies in managing diseases linked to its dysfunction. Overall, the study of recombinant SLC44A2 is vital for advancing our understanding of its contributions to human health and disease.

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