Analytical Data
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基因名
SLC43A1
- Application
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别名
L type amino acid transporter 3; L-type amino acid transporter 3; Large neutral amino acids transporter small subunit 3; LAT3_HUMAN; PB39 ; POV1 ; Prostate cancer overexpressed gene 1 protein; R00504 ; SLC43A1; Solute carrier family 43 member 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75387
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表达区间
1-559 aa
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氨基酸序列
MAPTLQQAYRRRWWMACTAVLENLFFSAVLLGWGSLLIILKNEGFYSSTCPAESSTNTTQDEQRRWPGCDQQDEMLNLGFTIGSFVLSATTLPLGILMDRFGPRPVRLVGSACFTASCTLMALASRDVEALSPLIFLALSLNGFGGICLTFTSLTLPNMFGNLRSTLMALMIGSYASSAITFPGIKLIYDAGVAFVVIMFTWSGLACLIFLNCTLNWPIEAFPAPEEVNYTKKIKLSGLALDHKVTGDLFYTHVTTMGQRLSQKAPSLEDGSDAFMSPQDVRGTSENLPERSVPLRKSLCSPTFLWSLLTMGMTQLRIIFYMAAVNKMLEYLVTGGQEHETNEQQQKVAETVGFYSSVFGAMQLLCLLTCPLIGYIMDWRIKDCVDAPTQGTVLGDARDGVATKSIRPRYCKIQKLTNAISAFTLTNLLLVGFGITCLINNLHLQFVTFVLHTIVRGFFHSACGSLYAAVFPSNHFGTLTGLQSLISAVFALLQQPLFMAMVGPLKGEPFWVNLGLLLFSLLGFLLPSYLFYYRARLQQEYAANGMGPLKVLSGSEVTA
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分子量
87.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC43A1 (Solute Carrier Family 43 Member 1) is a member of the solute carrier family, which plays a crucial role in the transport of various molecules across cellular membranes. Recent studies have highlighted its involvement in the transport of important metabolites, including essential amino acids and nucleosides, thereby suggesting its potential significance in various physiological and pathological processes, including cancer biology and drug resistance. The recombinant expression of SLC43A1 in heterologous systems is essential for elucidating its functional properties, substrate specificity, and transport mechanisms. Understanding these characteristics can provide insights into its role in cellular homeostasis and potential therapeutic applications. Moreover, the study of SLC43A1 has garnered attention due to its emerging implications in cancers, where altered expression levels may contribute to tumor growth and metastasis. The production of SLC43A1 recombinant protein allows researchers to explore these functions in detail, paving the way for the development of targeted therapies that could mitigate the effects of its dysregulation. As such, ongoing research efforts aim to characterize the recombinant SLC43A1 protein and its interactions at the molecular level, providing a deeper understanding of its biological significance and potential as a therapeutic target in various diseases.
