Analytical Data
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Gene name
SLC43A1
- Application
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Alternative Names
L type amino acid transporter 3; L-type amino acid transporter 3; Large neutral amino acids transporter small subunit 3; LAT3_HUMAN; PB39 ; POV1 ; Prostate cancer overexpressed gene 1 protein; R00504 ; SLC43A1; Solute carrier family 43 member 1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75387
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Expression Region
1-559 aa
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AA Sequence
MAPTLQQAYRRRWWMACTAVLENLFFSAVLLGWGSLLIILKNEGFYSSTCPAESSTNTTQDEQRRWPGCDQQDEMLNLGFTIGSFVLSATTLPLGILMDRFGPRPVRLVGSACFTASCTLMALASRDVEALSPLIFLALSLNGFGGICLTFTSLTLPNMFGNLRSTLMALMIGSYASSAITFPGIKLIYDAGVAFVVIMFTWSGLACLIFLNCTLNWPIEAFPAPEEVNYTKKIKLSGLALDHKVTGDLFYTHVTTMGQRLSQKAPSLEDGSDAFMSPQDVRGTSENLPERSVPLRKSLCSPTFLWSLLTMGMTQLRIIFYMAAVNKMLEYLVTGGQEHETNEQQQKVAETVGFYSSVFGAMQLLCLLTCPLIGYIMDWRIKDCVDAPTQGTVLGDARDGVATKSIRPRYCKIQKLTNAISAFTLTNLLLVGFGITCLINNLHLQFVTFVLHTIVRGFFHSACGSLYAAVFPSNHFGTLTGLQSLISAVFALLQQPLFMAMVGPLKGEPFWVNLGLLLFSLLGFLLPSYLFYYRARLQQEYAANGMGPLKVLSGSEVTA
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Molecular Weight
87.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SLC43A1 (Solute Carrier Family 43 Member 1) is a member of the solute carrier family, which plays a crucial role in the transport of various molecules across cellular membranes. Recent studies have highlighted its involvement in the transport of important metabolites, including essential amino acids and nucleosides, thereby suggesting its potential significance in various physiological and pathological processes, including cancer biology and drug resistance. The recombinant expression of SLC43A1 in heterologous systems is essential for elucidating its functional properties, substrate specificity, and transport mechanisms. Understanding these characteristics can provide insights into its role in cellular homeostasis and potential therapeutic applications. Moreover, the study of SLC43A1 has garnered attention due to its emerging implications in cancers, where altered expression levels may contribute to tumor growth and metastasis. The production of SLC43A1 recombinant protein allows researchers to explore these functions in detail, paving the way for the development of targeted therapies that could mitigate the effects of its dysregulation. As such, ongoing research efforts aim to characterize the recombinant SLC43A1 protein and its interactions at the molecular level, providing a deeper understanding of its biological significance and potential as a therapeutic target in various diseases.
