Analytical Data
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Gene name
CTNNAL1
- Application
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Alternative Names
ACRP; Alpha catenin related protein; alpha CATU; Alpha catulin; Alpha-catenin-related protein; Alpha-catulin; alpha2 catulin; catenin (cadherin associated protein); alpha like 1; Catenin alpha like protein 1; Catenin alpha-like protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UBT7
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Expression Region
1-734aa
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AA Sequence
MAASPGPAGV GGAGAVYGSG SSGFALDSGL EIKTRSVEQT LLPLVSQITT LINHKDNTKK SDKTLQAIQR VGQAVNLAVG RFVKVGEAIA NENWDLKEEI NIACIEAKQA GETIAALTDI TNLNHLESDG QITIFTDKTG VIKAARLLLS SVTKVLLLAD RVVIKQIITS RNKVLATMER LEKVNSFQEF VQIFSQFGNE MVEFAHLSGD RQNDLKDEKK KAKMAAARAV LEKCTMMLLT ASKTCLRHPN CESAHKNKEG VFDRMKVALD KVIEIVTDCK PNGETDISSI SIFTGIKEFK MNIEALRENL YFQSKENLSV TLEVILERME DFTDSAYTSH EHRERILELS TQARMELQQL ISVWIQAQSK KTKSIAEELE LSILKISHSL NELKKELHST ATQLAADLLK YHADHVVLKA LKLTGVEGNL EALAEYACKL SEQKEQLVET CRLLRHISGT EPLEITCIHA EETFQVTGQQ IISAAETLTL HPSSKIAKEN LDVFCEAWES QISDMSTLLR EINDVFEGRR GEKYGYLSLP KPMKNNANLK SLKPDKPDSE EQAKIAKLGL KLGLLTSDAD CEIEKWEDQE NEIVQYGRNM SSMAYSLYLF TRGEGPLKTS QDLIHQLEVF AAEGLKLTSS VQAFSKQLKD DDKLMLLLEI NKLIPLCHQL QTVTKTSLQN KVFLKVDKCI TKTRSMMALL VQLLSLCYKL LKKLQMENNG WVSVTNKDTM DSKT
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Molecular Weight
81.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CTNNAL1, or catenin alpha-like protein 1, is a key player in cell adhesion and signaling pathways, particularly in the context of cellular morphogenesis and stability. Recent studies have highlighted its roles in various biological processes, including cell proliferation, differentiation, and migration, suggesting its involvement in carcinogenesis and tumor progression. The protein interacts with the Wnt signaling pathway, which is critical for developmental processes and has been implicated in numerous cancers when dysregulated. Additionally, CTNNAL1 has been shown to bind to various proteins that affect cytoskeletal dynamics and cell motility, further underscoring its importance in maintaining cellular architecture and function. Recombinant protein studies of CTNNAL1 are essential for elucidating its specific molecular functions and interactions. Understanding the mechanisms by which CTNNAL1 influences cell behavior could provide valuable insights into potential therapeutic targets for cancer and other diseases associated with aberrant cell adhesion and signaling. As research continues to explore the multifaceted roles of CTNNAL1, the development of techniques to produce and study this recombinant protein is pivotal for advancing our knowledge in cellular biology and oncology.
