Cat: PAX2000-11417

Recombinant Human SLC2A10 Protein,GST

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Analytical Data

  • Gene name

    SLC2A10

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    AA450473 ; ATS; facilitated glucose transporter member 10; Glucose Transporter GLUT10; Glucose transporter type 10; glut 10; GLUT-10; GLUT10; GTR10_HUMAN; MGC126706 ; slc2a10; Solute carrier family 2; Solute carrier family 2 member 10; Solute carrier family 2. facilitated glucose transporter member 10

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    O95528

  • AA Sequence

    MGHSPPVLPLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQEFLVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLFLPAGTDETATHKDLIPLQGGEAPKLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMALSVSGIGLVSFAVPMDSGPSCLAVPNATGQTGLPGDSGLLQDSSLPPIPRTNEDQREPILSTAKKTKPHPRSGDPSAPPRLALSSALPGPPLPARGHALLRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKRRFTLSFGHRQNSTGIPYSRIEISAAS

  • Molecular Weight

    59.6 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SLC2A10, also known as GLUT10, is a member of the glucose transporter family, primarily involved in the transport of hexoses and other substrates across the plasma membrane of cells. The gene encoding SLC2A10 is associated with systemic conditions such as familial hyperuricemia and arterial calcification, highlighting its significance in human health. Recent studies have indicated that SLC2A10 may play a role in vascular smooth muscle cell function, influencing cellular metabolism and contributing to diseases like atherosclerosis and vascular aging. The characterization of SLC2A10 as a recombinant protein is essential for further understanding its structure-function relationship, substrate specificity, and interaction with other proteins. The production and study of SLC2A10 recombinant protein provide valuable insights into its biochemical properties and potential therapeutic implications. Through in vitro and in vivo experimental approaches, researchers aim to elucidate the physiological roles of SLC2A10, paving the way for novel strategies to address related cardiovascular and metabolic disorders.

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