Analytical Data
-
Gene name
SLC27A6
- Application
-
Alternative Names
SLC27A6; ACSVL2; FACVL2; FATP6; Long-chain fatty acid transport protein 6; FATP-6; Fatty acid transport protein 6; Arachidonate--CoA ligase; Fatty-acid-coenzyme A ligase. very long-chain 2; Solute carrier family 27 member 6; Very long-chain acyl-CoA synthetase homolog 1; VLCSH1; hVLCS-H1
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9Y2P4
-
Expression Region
1-619 aa
-
AA Sequence
MLLSWLTVLGAGMVVLHFVQKLLFTYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLIKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIKL
-
Molecular Weight
93.83 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SLC27A6, a member of the solute carrier family 27, encodes a fatty acid transport protein that plays a critical role in lipid homeostasis and cellular fatty acid uptake. Research on SLC27A6 has gained momentum due to its potential implications in various metabolic disorders, including obesity, diabetes, and cardiovascular diseases. This protein is primarily expressed in tissues such as the intestine and adipose tissue, highlighting its significance in lipid metabolism. Studies have shown that SLC27A6 facilitates the transport of long-chain fatty acids across cell membranes, which is essential for energy production and the synthesis of lipid-derived signaling molecules. Furthermore, alterations in SLC27A6 expression have been linked to metabolic dysregulation, making it a potential therapeutic target for addressing metabolic diseases. Understanding the structure and function of SLC27A6 through recombinant protein studies can provide insights into its transport mechanisms and interactions with fatty acids, paving the way for novel strategies to modulate its activity in disease contexts. Overall, the exploration of SLC27A6, particularly through the generation and characterization of its recombinant protein, holds promise for unraveling the complexities of lipid metabolism and developing targeted interventions for related health issues.
