Analytical Data
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Gene name
CTDSP2
- Application
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Alternative Names
Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 2; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; conserved gene amplified in osteosarcoma 4; conserved gene amplified in osteosarcoma; CTDS2_HUMAN; Ctdsp2; NIF2; NLI interacting factor 2; NLI-interacting factor 2; Nuclear LIM interactor interacting factor 2; Nuclear LIM interactor-interacting factor 2; OS4
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O14595
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Expression Region
1-271aa
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AA Sequence
MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRNIFKALFCCFRAQHVGQSSSSTELAAYKEEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRAP
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Molecular Weight
55.55 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CTDSP2 (C-Terminal Domain Phosphatase 2) is a crucial enzyme involved in the regulation of transcription and RNA processing through its phosphatase activity on the C-terminal domain (CTD) of RNA polymerase II. The research on CTDSP2 has gained significant attention due to its implications in various cellular processes, including gene expression, cell cycle regulation, and response to stress. Abnormalities in CTDSP2 expression levels have been associated with various diseases, including cancers and developmental disorders, highlighting its potential as a therapeutic target. Recent advancements in molecular biology techniques have allowed for a deeper understanding of its biochemical properties and interactions with other cellular proteins. Investigating the structure and function of recombinantly expressed CTDSP2 proteins can shed light on its role in cellular signaling pathways, ultimately contributing to the development of novel strategies for disease intervention. Moreover, by exploring the regulatory mechanisms that govern CTDSP2 activity, researchers aim to unravel its potential as a biomarker for disease progression and response to therapies. As a result, CTDSP2 is emerging as a focal point in the fields of molecular biology and medical research, where its study may lead to new insights into the intricate network of cellular regulation.
