Cat: PA2000-3256

Recombinant Human DENND1A Protein,His

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Analytical Data

  • Gene name

    DENND1A

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    DENND1A;FAM31A;KIAA1608;DENN domain-containing Protein 1A

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8TEH3

  • Expression Region

    1-559aa

  • AA Sequence

    MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKDPKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQNTIATPATLHILQKSITHFAAKFPTRGWTSSSH

  • Molecular Weight

    79.4 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

DENND1A (Differentially Expressed in Normal and Neoplastic Development 1A) is a protein known for its role in intracellular trafficking and signaling pathways, particularly in the context of cancer biology and reproductive health. Its involvement in various cellular processes has drawn attention, as alterations in its expression or function may contribute to the progression of various diseases, including cancer and infertility. Research has highlighted DENND1A's potential as a biomarker for certain tumors, making it a subject of interest for therapeutic strategies. The study of DENND1A recombinant protein aims to elucidate its structure-function relationship and interactions with other molecular partners. Utilizing techniques such as recombinant DNA technology and protein expression systems, researchers can produce DENND1A in sufficient quantities for functional assays and structural studies. Understanding the molecular mechanisms influenced by DENND1A could reveal new insights into tumorigenesis and provide avenues for the development of novel therapeutic interventions. Furthermore, as DENND1A is implicated in reproductive processes, research into its recombinant form also holds promise for advancing fertility treatments. Overall, the study of DENND1A recombinant protein is a vital step toward unraveling its biological significance and potential clinical applications.

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