Analytical Data
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基因名
SLC25A21
- Application
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别名
SLC25A21; ODC; Mitochondrial 2-oxodicarboxylate carrier; Solute carrier family 25 member 21
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BQT8
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表达区间
1-299 aa
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氨基酸序列
MSAKPEVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPALTFAIAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYSWLQENW
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分子量
59.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC25A21, a member of the solute carrier family, encodes a mitochondrial carrier protein involved in the transport of metabolites across the mitochondrial membrane. This protein plays a crucial role in mitochondrial function, specifically in the transport of key substances such as carnitine, which is vital for fatty acid metabolism and energy production. Mutations in the SLC25A21 gene have been associated with various metabolic disorders, highlighting its importance in cellular energy homeostasis. Research on recombinant SLC25A21 protein aims to elucidate its structure-function relationships and transport mechanisms, providing insights into its physiological roles and the consequences of its dysfunction. By expressing and characterizing this protein in heterologous systems, scientists can study its properties in detail, paving the way for potential therapeutic strategies to address conditions linked to SLC25A21 impairment. Such studies may also enhance our understanding of mitochondrial biology and its implications in human health and disease.
