Analytical Data
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基因名
BANP
- Application
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别名
BANP；BEND1；SMAR1；Protein BANP
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N9N5
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表达区间
1-519aa
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氨基酸序列
MMSEHDLADV VQIAVEDLSP DHPVVLENHV VTDEDEPALK RQRLEINCQD PSIKTICLRL DSIEAKLQAL EATCKSLEEK LDLVTNKQHS PIQVPMVAGS PLGATQTCNK VRCVVPQTTV ILNNDRQNAI VAKMEDPLSN RAPDSLENVI SNAVPGRRQN TIVVKVPGQE DSHHEDGESG SEASDSVSSC GQAGSQSIGS NVTLITLNSE EDYPNGTWLG DENNPEMRVR CAIIPSDMLH ISTNCRTAEK MALTLLDYLF HREVQAVSNL SGQGKHGKKQ LDPLTIYGIR CHLFYKFGIT ESDWYRIKQS IDSKCRTAWR RKQRGQSLAV KSFSRRTPNS SSYCPSEPMM STPPPASELP QPQPQPQALH YALANAQQVQ IHQIGEDGQV QVGHLHIAQV PQGEQVQITQ DSEGNLQIHH VGQDGQLLEA TRIPCLLAPS VFKASSGQVL QGAQLIAVAS SDPAAAGVDG SPLQGSDIQV QYVQLAPVSD HTAGAQTAEA LQPTLQPEMQ LEHGAIQIQ
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of BANP (Bcl-2 Associated Agonist of Cell Death Protein) recombinant protein is situated at the intersection of cancer research and apoptosis regulation. As a member of the Bcl-2 family, BANP plays a pivotal role in modulating cell survival and death, making it an essential focus for understanding tumorigenesis. In various cancers, the balance between pro-apoptotic and anti-apoptotic signals is often disrupted, leading to unchecked cell growth and resistance to therapy. By investigating BANP's role in these processes, researchers aim to uncover its potential as a therapeutic target. The production of recombinant BANP allows for detailed biochemical studies, enabling the analysis of its functional properties and interactions with other apoptotic proteins. Understanding how BANP influences cell fate could illuminate new strategies for promoting apoptosis in cancer cells, thereby enhancing the efficacy of existing treatments and potentially leading to the development of novel cancer therapies. The recombinant form of this protein not only facilitates structural and functional analyses but also provides a platform for screening potential inhibitors or activators, crucial for advancing targeted therapies aimed at restoring the apoptotic pathway in malignancies. Consequently, ongoing research aims to decipher the mechanistic pathways involving BANP, which could contribute significantly to the fields of cancer biology and therapeutic innovation.
