Analytical Data
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Gene name
TRIM69
- Application
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Alternative Names
TRIM69；RNF36；E3 ubiquitin-Protein ligase TRIM69
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86WT6
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Expression Region
1-341aa
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AA Sequence
MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ
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Molecular Weight
66.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TRIM69 is a member of the tripartite motif (TRIM) protein family, known for its roles in various cellular processes, including immune response, cell proliferation, and apoptosis. Recent studies have highlighted the significance of TRIM proteins in post-translational modifications, particularly ubiquitination, which is pivotal for regulating protein stability and function. TRIM69, in particular, has garnered attention due to its potential involvement in cancer biology and viral infections, where it may modulate cellular pathways that influence tumor growth and immune evasion. The expression and functional characterization of TRIM69 are vital for understanding its role in health and disease. Researchers are focusing on generating recombinant TRIM69 proteins to elucidate its biological functions and interactions with other cellular factors. Such studies could provide insight into the mechanisms underlying various pathologies and offer potential therapeutic targets for interventions. Moreover, the exploration of TRIM69's role in immune modulation may contribute to the development of novel strategies for combating viral diseases and enhancing vaccine efficacy. As the understanding of TRIM69 expands, its potential as a biomarker and therapeutic target in oncology and virology becomes increasingly promising.
