Analytical Data
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Gene name
SLAIN1
- Application
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Alternative Names
C13orf32; chromosome 13 open reading frame 32; FLJ30046; MGC131899; SLAI1_HUMAN; SLAIN motif family member 1; SLAIN motif family; member 1; SLAIN motif-containing protein 1; Slain1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8ND83
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Expression Region
1-568 aa
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AA Sequence
MMAEQVKCAS AGVSSGAGSG PVVNAELEVK KLQELVRKLE KQNEQLRSRA ASAAAAPHLL LLPPPPPAAP PPAGLQPLGP RSPPAATATA AASGGLGPAF PGTFCLPSPA PSLLCSLAQP PEAPFVYFKP AAGFFGAGGG GPEPGGAGTP PGAAAAPPSP PPTLLDEVEL LDLESVAAWR DEDDYTWLYI GSSKTFTSSE KSLTPLQWCR HVLDNPTPEM EAARRSLCFR LEQGYTSRGS PLSPQSSIDS ELSTSELEDD SISMGYKLQD LTDVQIMARL QEESLRQDYA STSASVSRHS SSVSLSSGKK GTCSDQEYDQ YSLEDEEEFD HLPPPQPRLP RCSPFQRGIP HSQTFSSIRE CRRSPSSQYF PSNNYQQQQY YSPQAQTPDQ QPNRTNGDKL RRSMPNLARM PSTTAISSNI SSPVTVRNSQ SFDSSLHGAG NGISRIQSCI PSPGQLQHRV HSVGHFPVSI RQPLKATAYV SPTVQGSSNM PLSNGLQLYS NTGIPTPNKA AASGIMGRSA LPRPSLAING SNLPRSKIAQ PVRSFLQPPK PLSSLSTLRD GNWRDGCY
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Molecular Weight
60.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SLAIN1, or SLAIN motif-containing protein 1, is a protein that plays a crucial role in cellular processes, particularly in the regulation of microtubule dynamics and cellular morphology. It is involved in several critical biological functions, including cell division, differentiation, and migration. Research on SLAIN1 has gained attention due to its implications in various diseases, including cancer, where dysregulation of microtubule dynamics can lead to uncontrolled cell proliferation and metastasis. Additionally, SLAIN1 has been implicated in the assembly of the mitotic spindle, a structure essential for accurate chromosome segregation during cell division. The protein interacts with microtubules and other cellular components, suggesting its potential as a novel therapeutic target. The study of SLAIN1 recombinant proteins allows for a better understanding of its function, interaction with other proteins, and role in cellular pathways, paving the way for potential biomedical applications. Researchers are particularly interested in elucidating the molecular mechanisms by which SLAIN1 influences cytoskeletal dynamics and identifying possible links to disease pathologies. Overall, the investigation of SLAIN1 and its recombinant forms is crucial for unraveling the complexities of cellular behavior and developing targeted therapies to combat diseases associated with its dysregulation.
