Analytical Data
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Gene name
RASSF6
- Application
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Alternative Names
RASSF6；Ras association domain-containing Protein 6
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6ZTQ3
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Expression Region
1-303aa
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AA Sequence
MTMMAHQYPSWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGMLDIFWGVKRPIQLKIQDEKPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMSEKRNSQEDYLSYHSNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRASINGHFYNHEIENSPQDFALHIIFATGEQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKREIQRIVTKFNKEKAIILKCLQNKLVIKTETTV
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Molecular Weight
62.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RASSF6 (Ras association domain family member 6) is a member of the Ras-association domain family, which is known for its involvement in various cellular processes, including cell proliferation, apoptosis, and tumor suppression. Research indicates that RASSF6 plays a crucial role in modulating signaling pathways associated with Ras proteins, which are pivotal in cancer development. Studies have shown that RASSF6 expression is often downregulated in various cancer types, suggesting a potential tumor-suppressive function. The protein has been implicated in cellular stress responses and may interact with other signaling molecules, thereby influencing key pathways that regulate cell survival and death. The understanding of RASSF6's biological functions and molecular mechanisms can provide insights into its role as a candidate biomarker for cancer diagnostics and therapy. Hence, the recombinant production of RASSF6 offers a valuable tool for investigating its structure-function relationships, interactions with other proteins, and effects on cellular behavior in both normal and pathological states, paving the way for potential therapeutic applications and the development of novel cancer treatments.
