Analytical Data
-
基因名
CORO2A
- Application
-
别名
CLIPINB; COR2A_HUMAN; CORO 2A; CORO2A; Coronin 2A; Coronin actin binding protein 2A; Coronin like protein B; Coronin-2A; DKFZp686G19226; IR10; OTTHUMP00000021767; OTTHUMP00000021768; WD protein IR10; WD repeat containing protein 2; WD repeat protein 2; WD repeat-containing protein 2; WDR2
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q92828
-
表达区间
1-525aa
-
氨基酸序列
MSWHPQYRSS KFRHVFGKPA SKENCYDSVP ITRSVHDNHF CAVNPHFIAV VTECAGGGAF LVIPLHQTGK LDPHYPKVCG HRGNVLDVKW NPFDDFEIAS CSEDATIKIW SIPKQLLTRN LTAYRKELVG HARRVGLVEW HPTAANILFS AGYDYKVMIW NLDTKESVIT SPMSTISCHQ DVILSMSFNT NGSLLATTCK DRKIRVIDPR AGTVLQEASY KGHRASKVLF LGNLKKLMST GTSRWNNRQV ALWDQDNLSV PLMEEDLDGS SGVLFPFYDA DTSMLYVVGK GDGNIRYYEV SADKPHLSYL TEYRSYNPQK GIGVMPKRGL DVSSCEIFRF YKLITTKSLI EPISMIVPRR SESYQEDIYP PTAGAQPSLT AQEWLSGMNR DPILVSLRPG SELLRPHPLP AERPIFNSMA PASPRLLNQT EKLAAEDGWR SSSLLEEKMP RWAAEHRLEE KKTWLTNGFD VFECPPPKTE NELLQMFYRQ QEEIRRLREL LTQREVQAKQ LELEIKNLRM GSEQL
-
分子量
83.49 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CORO2A, or Coronin 2A, is a member of the coronin protein family that plays a critical role in actin dynamics and cellular processes such as cytoskeletal organization, migration, and immune responses. Research on CORO2A has gained traction due to its involvement in various cellular functions and its potential link to pathological conditions, including cancer and autoimmune diseases. The protein is primarily expressed in hematopoietic cells and has been shown to regulate dendritic cell function and T-cell activation, highlighting its importance in the immune system. Understanding the structure and function of CORO2A through recombinant protein studies can provide insights into its mechanism of action and interactions with other cellular components. Moreover, recombinant CORO2A can serve as a valuable tool for investigating its role in cellular processes and developing therapeutic strategies targeting CORO2A-related pathways. Given its significant biological functions, the study of CORO2A not only contributes to our comprehension of fundamental cellular mechanisms but also opens new avenues for therapeutic interventions in diseases characterized by immune dysfunction or aberrant cell migration.
