Analytical Data
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基因名
TRIB2
- Application
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别名
TRIB2；TRB2；Tribbles homolog 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q92519
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表达区间
1-343aa
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氨基酸序列
MNIHRSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPE TPNLSHCVSC IGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQ ESLAPCFCLSAHSNINQITEII LGETKAYVFFERSYGDMHSFVRTCKK LREEEAARLFYQIASAVAHCHDGGLVLRDLKLRK FIFKDEERTRVKLE SLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSL GV MLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRRE PSERLTSQ EILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDP FFN
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分子量
64 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TRIB2, a member of the tribbles homolog family, is a pseudokinase that has garnered significant interest in the field of molecular biology and oncology due to its role in various cellular processes, including protein degradation, signaling pathways, and cell proliferation. Research indicates that TRIB2 is implicated in cancer progression, particularly in hematological malignancies, where it acts as an oncogene that promotes tumor growth and survival by modulating the activity of key signaling pathways, such as the NF-κB and MAPK pathways. The understanding of TRIB2's function has been further enhanced by the characterization of its protein interactions and its involvement in the regulation of other oncogenes and tumor suppressors. Recent studies utilizing TRIB2 recombinant proteins have provided insights into its molecular mechanisms, enabling researchers to investigate its potential as a therapeutic target. Additionally, ongoing investigations into the structural features of TRIB2 may reveal novel interactions that could inform drug design strategies. Overall, the study of TRIB2 and its recombinant proteins continues to be an exciting area of research with the potential to advance our understanding of cancer biology and contribute to the development of targeted therapies.
