Analytical Data
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基因名
SH3PX3
- Application
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别名
MGC32065; SH3 and PX domain containing 3; SH3 and PX domain containing protein 3; SH3 and PX domain-containing protein 3; SH3PX3; SH3PXD3C; SNX 30; SNX 33; SNX30; snx33; SNX33_HUMAN; Sorting nexin 33; Sorting nexin-33
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8WV41
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表达区间
1-574 aa
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氨基酸序列
MALKGRALYD FHSENKEEIS IQQDEDLVIF SETSLDGWLQ GQNSRGETGL FPASYVEIVR SGISTNHADY SSSPAGSPGA QVSLYNSPSV ASPARSGGGS GFLSNQGSFE EDDDDDWDDW DDGCTVVEEP RAGGLGTNGH PPLNLSYPGA YPSQHMAFRP KPPLERQDSL ASAKRGSVVG RNLNRFSCFV RSGVEAFILG DVPMMAKIAE TYSIEMGPRG PQWKANPHPF ACSVEDPTKQ TKFKGIKSYI SYKLTPTHAA SPVYRRYKHF DWLYNRLLHK FTVISVPHLP EKQATGRFEE DFIEKRKRRL ILWMDHMTSH PVLSQYEGFQ HFLSCLDDKQ WKMGKRRAEK DEMVGASFLL TFQIPTEHQD LQDVEDRVDT FKAFSKKMDD SVLQLSTVAS ELVRKHVGGF RKEFQKLGSA FQAISHSFQM DPPFCSEALN SAISHTGRTY EAIGEMFAEQ PKNDLFQMLD TLSLYQGLLS NFPDIIHLQK GAFAKVKESQ RMSDEGRMVQ DEADGIRRRC RVVGFALQAE MNHFHQRREL DFKHMMQNYL RQQILFYQRV GQQLEKTLRM YDNL
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分子量
65.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SH3PX3, also known as SH3 Domain-containing Protein 3, is an adaptor protein that plays a crucial role in various cellular processes, including signal transduction, endocytosis, and cytoskeletal organization. It is characterized by its SH3 (Src Homology 3) domain, which facilitates protein-protein interactions, allowing it to participate in the regulation of numerous signaling pathways. Research into SH3PX3 has gained momentum due to its potential implications in cancer biology and neurodegenerative diseases. Studies have indicated that SH3PX3 may influence tumor progression by modulating key signaling pathways associated with cell proliferation and survival. Additionally, its involvement in synaptic function and neuronal signaling highlights its importance in the context of neurological disorders. The recombinant expression of SH3PX3 protein allows researchers to investigate its structural properties, interaction with binding partners, and functional roles in cellular processes. Understanding the mechanisms by which SH3PX3 operates could provide insights into the development of targeted therapeutic strategies for diseases where SH3PX3 is implicated. As such, further exploration of SH3PX3 can enhance our knowledge of molecular interactions within cells and contribute to the advancement of biomedical research.
