Analytical Data
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Gene name
ACBD5
- Application
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Alternative Names
ACBD5；KIAA1996；Acyl-CoA-binding domain-containing Protein 5
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5T8D3
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Expression Region
1-461aa
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AA Sequence
MFQFHAGSWESWCCCCLIPADRPWDRGQHWQLEMADTRSVHETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKWDAWSSLGDMTKEEAMIAYVEEMKKIIETMPMTEKVEELLRVIGPFYEIVEDKKSGRSSDITSVRLEKISKCLEDLGNVLTSTPNAKTVNGKAESSDSGAESEEEEAQEEVKGAEQSDNDKKMMKKSADHKNLEVIVTNGYDKDGFVQDIQNDIHASSSLNGRSTEEVKPIDENLGQTGKSAVCIHQDINDDHVEDVTGIQHLTSDSDSEVYCDSMEQFGQEESLDSFTSNNGPFQYYLGGHSSQPMENSGFREDIQVPPGNGNIGNMQVVAVEGKGEVKHGGEDGRNNSGAPHREKRGGETDEFSNVRRGRGHRMQHLSEGTKGRQVGSGGDGERWGSDRGSRGSLNEQIALVLMRLQEDMQ
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Molecular Weight
67.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ACBD5, or Acyl-CoA Binding Domain 5, is a protein that plays a critical role in lipid metabolism and cellular homeostasis. Its involvement in the transport and metabolism of fatty acids, particularly in the context of energy storage and utilization, has garnered significant interest in the field of biochemistry and molecular biology. This protein is particularly noted for its acyl-CoA binding properties, which are essential for regulating the availability of fatty acids for various metabolic pathways. Research has revealed that ACBD5 is linked to various physiological processes, including inflammation, insulin sensitivity, and the functionality of cellular organelles such as mitochondria and peroxisomes. As alterations in lipid metabolism are associated with numerous metabolic disorders, including obesity and diabetes, understanding the mechanisms underlying ACBD5's function could provide insights into potential therapeutic targets. Additionally, ACBD5 is considered a promising biomarker for certain conditions related to metabolic dysregulation. The characterization of recombinant ACBD5 through various biochemical and biophysical techniques is crucial for elucidating its structure-function relationship and interactions with other cellular components. Overall, ongoing research aims to further define ACBD5's role in cellular metabolism and its implications in health and disease, fostering advancements in targeted therapies for metabolic disorders.
