Analytical Data
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Gene name
BCL2L15
- Application
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Alternative Names
BCL2L15；C1orf178；Bcl-2-like Protein 15
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5TBC7
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Expression Region
1-163aa
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AA Sequence
MKSSQTFEEQTECIVNTLLMDFLSPTLQVASRNLCCVDEVDSGEPCSFDVAIIAGRLRMLGDQFNGELEASAKNVIAETIKGQTGAILQNTVESLSKTWCAQDSSLAYERAFLAVSVKLLEYMAHIAPEVVGQVAIPMTGMINGNQAIREFIQGQGGWENLES
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Molecular Weight
44.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BCL2L15, also known as BCL2-like 15, is a member of the BCL2 family of proteins that plays a critical role in regulating apoptosis, cellular proliferation, and survival. Research into BCL2L15 has gained momentum due to its potential implications in various diseases, particularly in cancer. Aberrant expression of BCL2 family proteins is frequently observed in numerous malignancies, with BCL2L15 being implicated in the survival of certain cancer cells, making it a potential therapeutic target. Additionally, studies have suggested that BCL2L15 may be involved in immune responses and the maintenance of hematopoietic stem cells. Understanding the mechanisms by which BCL2L15 operates, including its interactions with other BCL2 family members and downstream signaling pathways, is essential for delineating its role in both normal physiology and pathological conditions. The reconstitution and functional analysis of BCL2L15 can provide insights into its biological function and therapeutic potential, paving the way for novel cancer treatments that aim to modulate apoptotic pathways effectively. Thus, the study of BCL2L15 as a recombinant protein offers promising avenues for the development of targeted therapies and enhances our understanding of apoptosis regulation within the broader context of tumor biology and immune health.
