Analytical Data
-
Gene name
SFXN5
- Application
-
Alternative Names
SFXN5; Sideroflexin-5
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q8TD22
-
AA Sequence
MADTATTASAAAASAASASSDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTERRLREAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAVGLNVLVQKANKFTPATRLLIQRFVPFPAVASANICNVVLMRYGELEEGIDVLDSDGNLVGSSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARPRLLLPVQSLVCLAAFGLALPLAISLFPQMSEIETSQLEPEIAQATSSRTVVYNKGL
-
Molecular Weight
37.4 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SFXN5, a member of the sideroflexin family of proteins, has garnered attention in recent years due to its potential role in cellular iron metabolism and mitochondrial function. Research has shown that SFXN5 may be involved in the transport of iron and the regulation of iron homeostasis, which is crucial for maintaining cellular health and preventing oxidative stress. Dysregulation of iron metabolism is linked to various diseases, including neurodegenerative disorders and cancer, highlighting the importance of understanding SFXN5's function. Given its location in the mitochondria, SFXN5 is also thought to play a role in mitochondrial dynamics and bioenergetics. Studies involving the recombinant expression of SFXN5 can provide insights into its specific biochemical properties and interactions. Moreover, exploring the structure-function relationship of this protein through techniques such as X-ray crystallography and cryo-electron microscopy may uncover its mechanism of action and identify potential therapeutic targets. As research progresses, SFXN5 may emerge as a key player in the intricate balance of iron metabolism and mitochondrial health, paving the way for novel interventions in diseases associated with metabolic dysfunctions.
