Cat: PAX2000-11253

Recombinant Human SFMBT1 Protein,GST

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Analytical Data

  • Gene name

    SFMBT1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    DKFZp434L243; MGC93349; OTTMUSP00000030378; OTTMUSP00000030379; OTTMUSP00000030381; Renal ubiquitous protein 1; RU1; Scm like with four mbt domains 1; Scm like with four MBT domains protein 1; Scm related gene containing four mbt domains; Scm related gene product containing four mbt domains; Scm-like with four MBT domains protein 1; SFMBT; SFMBT 1; Sfmbt1; SMBT1_HUMAN; Smr

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9UHJ3

  • Expression Region

    1-866 aa

  • AA Sequence

    MNGEQQLDADAGSGMEEVELSWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVRTDPETYWVATVITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLIGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVENIGGRLKLRYEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVKEEEEEPLPSYLFKDKQVIGIHTFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRPENHARRSFVCHADSPGIFPVQWSLKNGLHISPPPGYPSQDFDWADYLKQCGAEAAPQRCFPPLISEHEFKENMKLEAVNPILPEEVCVATITAVRGSYLWLQLEGSKKPIPECIVSVESMDIFPLGWCETNGHPLSTPRRARVYKQRKIAVVQPEKQVPSSRTVHEGLRNQELNSTESVMINGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVKTADRVTEFCRQTCIKLECCPNLFGPRMVLDKCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLACALKKASKRRKRRKNVFVHKKKRSSASVDNTPAGSPQGSGGEDEDDPDEGDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRIEVAERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN

  • Molecular Weight

    124.5 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

The SFMBT1 protein, a member of the SFMBT family, plays a crucial role in various biological processes, including stem cell regulation and differentiation. Research on SFMBT1 has gained significant attention due to its potential implications in developmental biology and cancer therapeutics. It is known to be involved in epigenetic regulation, particularly through its interactions with chromatin and influence on gene expression. Studies have indicated that SFMBT1 might contribute to the maintenance of pluripotency in embryonic stem cells, as well as to the progression of malignant tumors, making it a target of interest in oncology. Additionally, the recombinant form of SFMBT1 is essential for elucidating its functional mechanisms and understanding its biological pathways. Scientists aim to produce and characterize this recombinant protein to analyze its structural properties, binding affinities, and interactions with other molecular partners. Such studies are critical for unraveling the complexities of SFMBT1 in both normal physiology and disease states, ultimately paving the way for novel therapeutic strategies and biomarker discoveries in cancer research and regenerative medicine.

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