Analytical Data
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Gene name
PDLIM3
- Application
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Alternative Names
PDLIM3；ALP；PDZ and LIM domain Protein 3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q53GG5
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Expression Region
1-189aa
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AA Sequence
MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHNRRAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSPQKTGTTLNTSIIFGPNLS
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Molecular Weight
36.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PDLIM3, a member of the PDZ-LIM domain protein family, has garnered interest in recent years due to its potential roles in cellular signaling and transcriptional regulation. This protein is involved in several critical biological processes, including cell adhesion, proliferation, and differentiation. Research has shown that PDLIM3 can interact with various signaling molecules and actin-binding proteins, implicating it in the regulation of cytoskeletal dynamics and cellular architecture. Its expression is associated with the development of certain tissues, and dysregulation of PDLIM3 has been linked to various pathological conditions, including cardiac hypertrophy and cancer. Given its multifaceted roles and implications in disease, generating and studying recombinant PDLIM3 protein is crucial for elucidating its functional mechanisms and biological significance. Such studies may facilitate the development of novel therapeutic strategies targeting PDLIM3-related pathways, highlighting its potential as a biomarker or therapeutic target in relevant diseases. The recombinant protein can be utilized in various assays, including binding studies and functional assays, to further understand its interactions and effects within cellular contexts. Overall, the research on PDLIM3 and its recombinant forms holds promise for advancing our understanding of complex biological processes and disease mechanisms.
