Analytical Data
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Gene name
MBL1
- Application
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Alternative Names
MBL1；MBD3L；Methyl-CpG-binding domain Protein 3-like 1
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Species
Rat
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P19999
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Expression Region
18-238
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AA Sequence
SGS QTCEETLKTC SVIACGRDGR DGPKGEKGEP GQGLRGLQGP PGKLGPPGSV GAPGSQGPKG QKGDRGDSRA IEVKLANMEA EINTLKSKLE LTNKLHAFSM GKKSGKKFFV TNHERMPFSK VKALCSELRG TVAIPRNAEE NKAIQEVAKT SAFLGITDEV TEGQFMYVTG GRLTYSNWKK DEPNDHGSGE DCVTIVDNGL WNDISCQASH TAVCEFPA
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MBL1 (Mannose-Binding Lectin 1) is a crucial protein involved in the innate immune response, playing a vital role in the recognition and clearance of pathogens. Research into MBL1 has gained significant attention due to its ability to bind to specific carbohydrate patterns on the surface of various microorganisms, thereby facilitating opsonization and enhancing phagocytosis by immune cells. Given its role in host defense, variations in the MBL1 gene have been linked to susceptibility to infectious diseases and autoimmune conditions. Additionally, MBL1 has been investigated for its potential therapeutic applications, including its use as a biomarker for disease states. Studies have shown that recombinant forms of MBL1 can exhibit enhanced immune responses, making it a candidate for immunotherapeutic strategies. The exploration of MBL1's structure-function relationship and its interactions with other immune components continues to be a promising area of research, enhancing our understanding of its role in health and disease and guiding the development of novel therapeutic interventions.
