Analytical Data
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基因名
REG3A
- Application
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别名
REG3A；HIP；PAP；PAP1；Regenerating islet-derived Protein 3-alpha
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种属
Mouse
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O09037
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表达区间
1-175aa
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氨基酸序列
MLPHLVLNSI SWMLLSCLLF VFQVQGEDFQ KEVPSPRTSC PMGYKAYRSH CYALVMTPKS WFQADLVCQK RPSGHLVSIL SGGEASFVSS LVNGRVDNYQ DIWIGLHDPT MGQQPNGGGW EWSNSDVLNY LNWDGDPSST VNRGHCGSLT ASSGFLKWGD YYCDGTLPFV CKFKQ
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分子量
18 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
REG3A, also known as regenerating islet-derived 3 alpha, is a member of the Reg family of proteins associated with various physiological and pathological processes. Originally identified for its role in pancreatic beta-cell regeneration, REG3A has garnered significant attention due to its involvement in inflammatory responses and its protective effects in the gastrointestinal tract. Elevated expression of REG3A has been observed in conditions such as inflammatory bowel disease and other gastrointestinal disorders, suggesting its potential as a biomarker for inflammation and tissue injury. Furthermore, REG3A exhibits antimicrobial properties, particularly against Gram-positive bacteria, highlighting its role in the innate immune system. Research has increasingly focused on elucidating the molecular mechanisms underlying REG3A’s actions, including its interaction with various signaling pathways and its effects on cell proliferation and apoptosis. Given its multifaceted roles, REG3A has emerged as a promising target for therapeutic interventions aimed at treating conditions characterized by inflammation and tissue damage. Studies exploring REG3A’s potential have implications not only for gastrointestinal health but also for broader applications in regenerative medicine and immune response modulation.
