Analytical Data
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Gene name
GALNT2
- Application
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Alternative Names
GALNT2；MUC5；Mucin-5AC
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q10471-1
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Expression Region
52-571aa
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AA Sequence
KKKDLHHSNG EEKAQSMETL PPGKVRWPDF NQEAYVGGTM VRSGQDPYAR NKFNQVESDK LRMDRAIPDT RHDQCQRKQW RVDLPATSVV ITFHNEARSA LLRTVVSVLK KSPPHLIKEI ILVDDYSNDP EDGALLGKIE KVRVLRNDRR EGLMRSRVRG ADAAQAKVLT FLDSHCECNE HWLEPLLERV AEDRTRVVSP IIDVINMDNF QYVGASADLK GGFDWNLVFK WDYMTPEQRR SRQGNPVAPI KTPMIAGGLF VMDKFYFEEL GKYDMMMDVW GGENLEISFR VWQCGGSLEI IPCSRVGHVF RKQHPYTFPG GSGTVFARNT RRAAEVWMDE YKNFYYAAVP SARNVPYGNI QSRLELRKKL SCKPFKWYLE NVYPELRVPD HQDIAFGALQ QGTNCLDTLG HFADGVVGVY ECHNAGGNQE WALTKEKSVK HMDLCLTVVD RAPGSLIKLQ GCRENDSRQK WEQIEGNSKL RHVGSNLCLD SRTAKSGGLS VEVCGPALSQ QWKFTLNLQQ
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Molecular Weight
62 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GALNT2, a member of the polypeptide N-acetylgalactosaminyltransferase family, plays a crucial role in the post-translational modification of proteins through O-glycosylation. This enzyme is responsible for transferring N-acetylgalactosamine (GalNAc) to serine or threonine residues on target proteins, which is a critical step in the synthesis of mucin-type glycoproteins. Research has shown that GALNT2 is implicated in various biological processes, including cell adhesion, signal transduction, and immune response, making it a significant focus in studies related to cancer, metabolic disorders, and cardiovascular diseases. Abnormal expression or activity of GALNT2 has been linked to pathological conditions, such as obesity and type 2 diabetes, highlighting its potential as a therapeutic target or biomarker. Recent advancements in recombinant protein technology have enabled the production of GALNT2 for functional studies, allowing researchers to investigate its structure-function relationships and interactions with other cellular components. Understanding the role of GALNT2 in disease mechanisms could pave the way for novel intervention strategies, thus reinforcing its importance in biomedical research.
