Analytical Data
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基因名
SDCCAG10
- Application
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别名
Antigen NY CO10; Antigen NY-CO-10; CWC27; CWC27 spliceosome associated protein homolog (S. cerevisiae); CWC27 spliceosome associated protein homolog S cerevisiae; CWC27_HUMAN; NY CO 10; NY-CO-10; peptidyl prolyl cis trans isomerase CWC27 homolog; Peptidyl prolyl cis trans isomerase SDCCAG10; Peptidyl-prolyl cis-trans isomerase CWC27 homolog; PPIase CWC27; PPIase SDCCAG10; SDCCAG10; Serologically defined colon cancer antigen 10
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6UX04
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表达区间
2-472 aa
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氨基酸序列
SNIYIQEPP TNGKVLLKTT AGDIDIELWS KEAPKACRNF IQLCLEAYYD NTIFHRVVPG FIVQGGDPTG TGSGGESIYG APFKDEFHSR LRFNRRGLVA MANAGSHDNG SQFFFTLGRA DELNNKHTIF GKVTGDTVYN MLRLSEVDID DDERPHNPHK IKSCEVLFNP FDDIIPREIK RLKKEKPEEE VKKLKPKGTK NFSLLSFGEE AEEEEEEVNR VSQSMKGKSK SSHDLLKDDP HLSSVPVVES EKGDAPDLVD DGEDESAEHD EYIDGDEKNL MRERIAKKLK KDTSANVKSA GEGEVEKKSV SRSEELRKEA RQLKRELLAA KQKKVENAAK QAEKRSEEEE APPDGAVAEY RREKQKYEAL RKQQSKKGTS REDQTLALLN QFKSKLTQAI AETPENDIPE TEVEDDEGWM SHVLQFEDKS RKVKDASMQD SDTFEIYDPR NPVNKRRREE SKKLMREKKE RR
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分子量
53.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SDCCAG10, a protein associated with the centrosome, is implicated in various cellular processes, including cell division and cilia formation. Disruptions in centrosomal function and ciliary structure are linked to a range of diseases, such as cancer and ciliopathies. Recent studies have focused on the role of SDCCAG10 in cell cycle regulation and its potential involvement in tumorigenesis, as altered expression levels may contribute to oncogenic pathways. Furthermore, SDCCAG10 has been identified as a critical factor in the stability and functionality of the primary cilium, which is pivotal for cellular signaling and homeostasis. Understanding the molecular mechanisms underlying SDCCAG10 function can unravel its contributions to both normal physiology and disease states. Research on SDCCAG10 could not only enhance our comprehension of centrosomal biology but also pave the way for novel therapeutic strategies targeting related disorders. As such, the recombinant expression and characterization of SDCCAG10 are crucial for elucidating its structural and functional properties, enabling further investigation into its role in health and disease.
