Cat: PAX2000-11163

Recombinant Human SCNM1 Protein,His

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Analytical Data

  • 基因名

    SCNM1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    SCNM1; Sodium channel modifier 1

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9BWG6

  • 表达区间

    1-230 aa

  • 氨基酸序列

    MSFKREGDDW SQLNVLKKRR VGDLLASYIP EDEALMLRDG RFACAICPHR PVLDTLAMLT AHRAGKKHLS SLQLFYGKKQ PGKERKQNPK HQNELRREET KAEAPLLTQT RLITQSALHR APHYNSCCRR KYRPEAPGPS VSLSPMPPSE VKLQSGKISR EPEPAAGPQA EESATVSAPA PMSPTRRRAL DHYLTLRSSG WIPDGRGRWV KDENVEFDSD EEEPPDLPLD

  • 分子量

    25.9 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SCNM1, or Suppressor of Chromosomal Instability 1, is a protein that has garnered significant interest due to its potential role in maintaining genomic stability and its implications in cancer biology. Characterized by a unique structure and functional motifs, SCNM1 is involved in various cellular processes, including regulation of gene expression and modulation of chromosomal stability during cell division. Recent studies have shown that anomalies in SCNM1 expression or function can lead to increased chromosomal instability, which is a hallmark of many cancers. Understanding the mechanistic pathways involving SCNM1 can reveal crucial insights into tumorigenesis and may offer new therapeutic targets. Researchers are focusing on the recombinant expression of SCNM1 to explore its biochemical properties, interactions with other proteins, and its effects on cellular functions. By employing advanced techniques such as X-ray crystallography and nuclear magnetic resonance (NMR), scientists aim to elucidate the three-dimensional structure of SCNM1 and understand how specific mutations may alter its function. This research not only enhances our knowledge of SCNM1's biological role but also opens avenues for the development of targeted therapies that could mitigate tumorigenic processes influenced by this protein. The study of recombinant SCNM1 thus stands at the intersection of molecular biology and clinical application, highlighting its significance in both fundamental research and potential therapeutic advancements.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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