Analytical Data
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基因名
CHD9
- Application
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别名
CHD9; KIAA0308; KISH2; PRIC320; AD-013; x0008Chromodomain-helicase-DNA-binding Protein 9; CHD-9; EC 3.6.4.12; ATP-dependent helicase CHD9
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q3L8U1
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表达区间
1-119
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氨基酸序列
MLINLLVAQLNMCYLHTLSLIVLQSIPKTNPMVCFQMYQMAVQCGAIRQLLPFQIKMDLLFTNKDIHTLCIKIKALWHTMTLPYFRPMNNKHSVLHYAHNKTEIISTQGRILLASLKIL
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分子量
38.83 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CHD9, a member of the chromodomain helicase DNA-binding (CHD) protein family, plays a critical role in chromatin remodeling and gene regulation. Its involvement in various cellular processes makes it a significant focus of research. Studies have shown that CHD9 is essential for maintaining cellular homeostasis and influencing developmental pathways. Dysregulation or mutations in CHD9 have been associated with several diseases, including cancer and autoimmune disorders, highlighting its potential as a therapeutic target. Recombination and characterization of CHD9 protein have provided insights into its functional domains and interaction partners, thereby elucidating its mechanisms of action within the nucleus. Researchers aim to understand CHD9’s role in chromatin organization, transcriptional regulation, and its response to environmental cues, as well as its impact on cellular stress responses. Through recombinant protein technology, scientists are investigating CHD9's biochemical properties and its interactions with histones and other chromatin-associated proteins. This research not only furthers our understanding of epigenetic regulation but also opens avenues for developing novel therapeutic strategies that leverage the manipulation of CHD9 activity in various diseases.












