Analytical Data
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基因名
SRSF10
- Application
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别名
SRSF10；KIAA1966；YT521；YTH domain-containing Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75494
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表达区间
1-183aa
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氨基酸序列
MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNTQYSSAYYTSRKI
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分子量
38.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SRSF10, a member of the serine/arginine-rich splicing factor (SRSF) family, plays a critical role in pre-mRNA splicing and regulation of gene expression. This protein is known for its involvement in alternative splicing, which is crucial for generating protein diversity and regulating various cellular functions. Research on SRSF10 has gained significance due to its potential implications in cancer biology, where dysregulation of splicing factors can lead to aberrant splicing patterns and contribute to tumorigenesis. It has been observed that SRSF10 can influence the expression of genes involved in cell proliferation, apoptosis, and other key pathways associated with cancer progression. Furthermore, studies have shown that SRSF10 interacts with various co-factors and is modulated by post-translational modifications, highlighting its complex regulatory networks. Understanding the function and regulation of SRSF10 may provide insights into potential therapeutic targets for cancer treatment, as well as a broader understanding of splicing mechanisms in normal and disease contexts. Consequently, SRSF10 has emerged as a subject of interest in molecular biology and cancer research, prompting further investigations into its precise molecular mechanisms and potential clinical applications.
