Analytical Data
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Gene name
RWDD2A
- Application
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Alternative Names
1700030C20Rik; AI848608; dJ747H23.2; MGC13523; MGC138208; MGC144625; MGC144626; OTTHUMP00000016790; OTTHUMP00000040569; RWD domain containing 2; RWD domain containing 2A; RWD domain-containing protein 2A; RWD2A_HUMAN; Rwdd2; Rwdd2a; Rwdd2a RWD domain containing 2A
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UIY3
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Expression Region
1-292 aa
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AA Sequence
MSASVKESLQ LQLLEMEMLF SMFPNQGEVK LEDVNALTNI KRYLEGTREA LPPKIEFVIT LQIEEPKVKI DLQVTMPHSY PYVALQLFGR SSELDRHQQL LLNKGLTSYI GTFDPGELCV CAAIQWLQDN SASYFLNRKL VYEPSTQAKP VKNTFLRMWI YSHHIYQQDL RKKILDVGKR LDVTGFCMTG KPGIICVEGF KEHCEEFWHT IRYPNWKHIS CKHAESVETE GNGEDLRLFH SFEELLLEAH GDYGLRNDYH MNLGQFLEFL KKHKSEHVFQ ILFGIESKSS DS
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Molecular Weight
33.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RWDD2A (RWD Domain Containing 2A) is a member of the RWD protein family, which is characterized by the presence of a highly conserved RWD domain. This family of proteins is believed to play crucial roles in various cellular processes, including protein folding, DNA repair, and the regulation of gene expression. Recent studies have indicated that RWDD2A is implicated in several biological pathways and has potential connections to disease mechanisms, particularly in cancer and neurodegenerative disorders. The protein's function appears to involve interactions with ubiquitin, suggesting a role in the ubiquitin-proteasome system, which is critical for maintaining cellular proteostasis. Research has focused on elucidating its structural properties and understanding its molecular interactions in order to uncover its biological significance. Given the potential impact of RWDD2A on cell biology and disease, recombinant protein studies have been initiated to facilitate functional assays and therapeutic exploration. Understanding RWDD2A at a molecular level could lead to new insights into its role in health and disease, paving the way for innovative approaches to treatment strategies targeting its pathways.
