Cat: PA2000-2961

Recombinant E.coli lush Protein,His

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Analytical Data

  • Gene name

    lush

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    lush;LIM/homeobox Protein Lhx8

  • Species

    E.coli

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    O02372

  • Expression Region

    30-153aa

  • AA Sequence

    MTMEQFLTSLDMIRSGCAPKFKLKTEDLDRLRVGDFNFPPSQDLMCYTKCVSLMAGTVNKKGEFNAPKALAQLPHLVPPEMMEMSRKSVEACRDTHKQFKESCERVYQTAKCFSENADGQFMWP

  • Molecular Weight

    19.2 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Lush, a member of the GPCR (G protein-coupled receptor) family, plays a crucial role in various physiological processes, particularly in the development of sensory organs and the regulation of signaling pathways in organisms like Drosophila. Research into Lush's function and structure has gained momentum due to its implications in understanding fundamental biological mechanisms and potential links to diseases. As a significant player in the olfactory and taste perception pathways, Lush contributes to the modulation of neuronal responses to external stimuli. Advances in molecular biology techniques have enabled scientists to investigate the protein's conformational dynamics, ligand interactions, and downstream signaling effects. The study of Lush not only enhances our comprehension of GPCR biology but also opens avenues for drug discovery, as targeting such receptors has been a successful strategy in treating various conditions. Furthermore, elucidating Lush's role in sensory signaling can provide insights into the evolutionary conservation of GPCR-mediated pathways across species, fostering a deeper understanding of both basic and applied biological sciences.

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