Analytical Data
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Gene name
RUNDC2A
- Application
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Alternative Names
SNX29; RUNDC2A; Sorting nexin-29; RUN domain-containing protein 2A
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TEQ0
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Expression Region
1-249 aa
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AA Sequence
MDEERSSMLPTMAAGPNSILFAINIDNKDLNGQSKFAPTVSDLLKESTQNVTLLKESTQGVSSVFREITASSAISILIKPEQETDPLPVVSRNVSADAKCKKERKKKKQVTNIISFDDEEDEQNSGDMFKKTPGAGESSEDNSDHSSVNIMSAFESPFGPNSNGSQSSNSWKIDSLSLNREFGYQKLDVKSIDDEDVDENEDDVYGNSSGRKHRGHSESPEKNGAHSVTQAGVQWHDLGSLQPLPPGFR
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Molecular Weight
53.13 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RUNDC2A is an emerging protein of interest due to its potential role in cellular signaling and regulation. As a member of the RUN domain-containing protein family, RUNDC2A has been implicated in various biological processes, including cellular proliferation, apoptosis, and differentiation. Previous studies have highlighted its involvement in cancer progression and immune response, suggesting that RUNDC2A may serve as a crucial mediator in these pathways. The protein's distinctive structure, featuring a RUN domain, suggests its ability to interact with other molecular partners, thus influencing signaling cascades. Recent advancements in proteomics and molecular biology techniques have facilitated the exploration of RUNDC2A's functions and interactions at a cellular level. Understanding the mechanisms associated with RUNDC2A is vital, as it may contribute to the development of novel therapeutic strategies for diseases marked by aberrant signaling pathways, particularly in cancer biology. Consequently, research into the biochemistry and functional roles of RUNDC2A is gaining momentum, aiming to unravel its potential as a biomarker or a target for therapeutic intervention.
