Analytical Data
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Gene name
RUNDC1
- Application
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Alternative Names
RUNDC1; LP5161; RUN domain-containing protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96C34
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Expression Region
1-613 aa
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AA Sequence
MAAVEAAAEP VTVVAAVGPK AKDEEEEEEE PLPPCEAVRW APVGAVAEAR PGATAFLEEA TAEEPGAAPG SPPDSPGRTL RRLRAERRRL DSALLALSSH FAQVQFRLRQ VVRGAPAEQQ RLLRELEDFA FRGCPHVLGY EGPGDPASDE GDGLPGDRPW LRGEDQSEQE KQERLETQRE KQKELILQLK TQLDDLETFA YQEGSYDSLP QSVVLERQRV IIDELIKKLD MNLNEDISSL STEELRQRVD AAVAQIVNPA RVKEQLVEQL KTQIRDLEMF INFIQDEVGS PLQTGGGHCE CKAGGKTGNG CSRTGSSRTP PGNSKTKAED VKKVRETGLH LMRRALAVLQ IFAVSQFGCA TGQIPPTLWQ RVQADRDYSP LLKRLEVSVD RVKQLALRQQ PHDHVITSAN LQDLSLGGKD ELTMAVRKEL TVAVRDLLAH GLYASSPGMS LVMAPIACLL PAFSSAPEAM HPWELFVKYY HAKNGRAYVE SPARKLSQSF ALPVTGGTVV TPKQSLLTAI HMVLTEHDPF KRSADSELKA LVCMALNEQR LVSWVNLICK SGSLIEPHYQ PWSYMAHTGF ESALNLLSRL SSLKFSLPVD LAVRQLKNIK DAF
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Molecular Weight
67.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RUNDC1 (RUN domain-containing protein 1) is a protein implicated in various cellular processes, including cell proliferation, differentiation, and stress responses. Research into RUNDC1 has gained momentum due to its potential role in cancer biology and its association with several pathological conditions. Initial studies have indicated that RUNDC1 may function as a negative regulator of cellular growth, positioning it as a potential tumor suppressor. Its specific interaction with various signaling pathways highlights its importance in maintaining cellular homeostasis. Moreover, recent investigations have explored RUNDC1's involvement in the regulation of autophagy, a critical process for cellular quality control and response to nutrient deprivation. Given these multifaceted roles, the recombinant expression of RUNDC1 offers a valuable avenue for studying its structural and functional properties in vitro. Understanding the precise mechanisms by which RUNDC1 influences cellular behavior could provide insights into novel therapeutic strategies for diseases characterized by dysregulated cellular signaling. The recombinant protein can be utilized for biochemical assays, interaction studies, and structural analyses, ultimately enhancing our comprehension of RUNDC1's functions and its potential applications in medical research.
