Analytical Data
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Gene name
CDR2L
- Application
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Alternative Names
Paraneoplastic 62 kDa antigen
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86X02
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Expression Region
1-465aa
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AA Sequence
MRRAAGMEDFSAEEEESWYDQQDLEQDLHLAAELGKTLLERNKELEGSLQQMYSTNEEQVQEIEYLTKQLDTLRHVNEQHAKVYEQLDLTARDLELTNHRLVLESKAAQQKIHGLTETIERLQAQVEELQAQVEQLRGLEQLRVLREKRERRRTIHTFPCLKELCTSPRCKDAFRLHSSSLELGPRPLEQENERLQTLVGALRSQVSQERQRKERAEREYTAVLQEYSELERQLCEMEACRLRVQELEAELLELQQMKQAKTYLLGPDDHLAEALLAPLTQAPEADDPQPGRGDDLGAQDGVSSPAASPGHVVRKSCSDTALNAIVAKDPASRHAGNLTLHANSVRKRGMSILREVDEQYHALLEKYEELLSKCRQHGAGVRHAGVQTSRPISRDSSWRDLRGGEEGQGEVKAGEKSLSQHVEAVDKRLEQSQPEYKALFKEIFSRIQKTKADINATKVKTHSSK
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Molecular Weight
60.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CDR2L (Cell Cycle-Dependent Protein 2-Like) is a member of the CDR family of proteins that plays a critical role in cellular processes including cell cycle regulation, particularly during meiosis and mitosis. Recent studies have highlighted its involvement in various biological functions such as chromatin remodeling, DNA repair, and gene expression regulation. Research into CDR2L's role in human health has gained traction, as alterations in its expression or function have been linked to several diseases, including cancers and genetic disorders. Specifically, the dysregulation of CDR2L has been associated with tumorigenesis, making it a potential biomarker for cancer diagnosis and a target for therapeutic intervention. Additionally, as the understanding of CDR2L's structure and function expands, the recombinant protein produced for research purposes could facilitate the study of its interactions with other cellular molecules, elucidate the mechanisms of its action, and assist in developing novel strategies for treating diseases linked to its dysfunction. Efforts to characterize the CDR2L recombinant protein include analyzing its biochemical properties, cellular localization, and functional assays to determine its role in cellular pathways. Overall, the study of CDR2L and its recombinant protein is critical for advancing our knowledge of cell cycle regulation and its implications in disease progression.
