Analytical Data
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Gene name
JAML
- Application
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Alternative Names
JAML；AMICA1；Junctional adhesion molecule-like
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86YT9-1
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Expression Region
1-275aa
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AA Sequence
MFCPLKLILL PVLLDYSLGL NDLNVSPPEL TVHVGDSALM GCVFQSTEDK CIFKIDWTLS PGEHAKDEYV LYYYSNLSVP IGRFQNRVHL MGDILCNDGS LLLQDVQEAD QGTYICEIRL KGESQVFKKA VVLHVLPEEP KELMVHVGGL IQMGCVFQST EVKHVTKVEW IFSGRRAKEE IVFRYYHKLR MSVEYSQSWG HFQNRVNLVG DIFRNDGSIM LQGVRESDGG NYTCSIHLGN LVFKKTIVLH VSPEEPRTLV TPAALRPLVL GGNQL
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Molecular Weight
31 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
JAML (Junctional Adhesion Molecule-Like) is a member of the immunoglobulin superfamily and has garnered significant interest in recent years due to its crucial role in immune responses and cell communication. Found primarily in hematopoietic tissues, JAML functions as an adhesion molecule that mediates the interaction between immune cells and their microenvironment, particularly in lymphocyte migration and activation. Its involvement in various physiological and pathological processes, including inflammation, autoimmunity, and cancer, makes it a potential target for therapeutic interventions. Current research is focused on understanding the structural and functional characteristics of JAML, as well as elucidating its mechanisms of action in immune cell signaling and tissue homeostasis. The development of recombinant JAML proteins aims to provide insights into its biological functions and interactions, offering new avenues for the treatment of immune-related diseases. By employing techniques such as protein engineering and molecular modeling, researchers seek to optimize JAML-based biotherapies, potentially leading to innovative strategies for modulating immune responses and enhancing therapeutic efficacy.
