Analytical Data
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基因名
JAML
- Application
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别名
JAML；AMICA1；Junctional adhesion molecule-like
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q86YT9-1
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表达区间
1-275aa
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氨基酸序列
MFCPLKLILL PVLLDYSLGL NDLNVSPPEL TVHVGDSALM GCVFQSTEDK CIFKIDWTLS PGEHAKDEYV LYYYSNLSVP IGRFQNRVHL MGDILCNDGS LLLQDVQEAD QGTYICEIRL KGESQVFKKA VVLHVLPEEP KELMVHVGGL IQMGCVFQST EVKHVTKVEW IFSGRRAKEE IVFRYYHKLR MSVEYSQSWG HFQNRVNLVG DIFRNDGSIM LQGVRESDGG NYTCSIHLGN LVFKKTIVLH VSPEEPRTLV TPAALRPLVL GGNQL
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分子量
31 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
JAML (Junctional Adhesion Molecule-Like) is a member of the immunoglobulin superfamily and has garnered significant interest in recent years due to its crucial role in immune responses and cell communication. Found primarily in hematopoietic tissues, JAML functions as an adhesion molecule that mediates the interaction between immune cells and their microenvironment, particularly in lymphocyte migration and activation. Its involvement in various physiological and pathological processes, including inflammation, autoimmunity, and cancer, makes it a potential target for therapeutic interventions. Current research is focused on understanding the structural and functional characteristics of JAML, as well as elucidating its mechanisms of action in immune cell signaling and tissue homeostasis. The development of recombinant JAML proteins aims to provide insights into its biological functions and interactions, offering new avenues for the treatment of immune-related diseases. By employing techniques such as protein engineering and molecular modeling, researchers seek to optimize JAML-based biotherapies, potentially leading to innovative strategies for modulating immune responses and enhancing therapeutic efficacy.
