Cat: PA1000-6320

Recombinant Human BAFFR Protein,His

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Analytical Data

  • 基因名

    BAFFR

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    BAFFR;BAFFR;BR3;;Tumor necrosis factor receptor superfamily member 13C

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q96RJ3

  • 表达区间

    2-71aa

  • 氨基酸序列

    RRGPRSLRGRDAPAPTPCVPAECFDLLVRHCVACGLLRTPRPKPAGASSP APRTALQPQESVGAGAGEAA

  • 分子量

    40 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

BAFFR (B-cell Activating Factor Receptor) is a critical receptor involved in the regulation of B cell function and survival, playing a pivotal role in immune responses. It specifically binds to BAFF (B-cell Activating Factor), a cytokine that promotes B cell maturation and persistence. The study of BAFFR is particularly important due to its implications in autoimmune diseases, such as systemic lupus erythematosus and rheumatoid arthritis, where dysregulation of B cells contributes to pathogenesis. Researchers have focused on the recombinant expression of BAFFR to understand its structural and functional properties, which can aid in the development of targeted therapies. By characterizing the interactions between BAFFR and its ligands, scientists aim to delineate the signaling pathways involved in B cell activation and differentiation. Moreover, recombinant BAFFR proteins serve as valuable tools in drug discovery, enabling the screening of compounds that may modulate its activity. This research not only enhances our understanding of the immune system but also opens up potential therapeutic avenues for treating B cell-related disorders. As a result, investigations into BAFFR and its recombinant forms are at the forefront of immunological research, promising insights into both basic biology and clinical applications.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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