Analytical Data
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基因名
RPL41
- Application
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别名
RPL41; 60S ribosomal protein L41; HG12; Large ribosomal subunit protein eL41
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P62945
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表达区间
1-25 aa
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氨基酸序列
MRAKWRKKRM RRLKRKRRKM RQRSK
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分子量
3.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RPL41 is a gene that encodes a ribosomal protein, which is a critical component of the ribosome, the cellular machinery responsible for protein synthesis. Studies have shown that RPL41 plays a significant role in ribosome assembly and function, influencing cellular growth and proliferation. Recent research has unearthed its potential involvement in various diseases, including cancer, where altered expression of ribosomal proteins can lead to dysregulated protein synthesis and cellular metabolism. Understanding the molecular mechanisms underlying RPL41's function could provide insights into ribosome biogenesis and the pathogenesis of ribosomopathies, a group of disorders arising from defects in ribosomal components. Moreover, since ribosomal proteins like RPL41 are highly conserved across species, they present an intriguing target for study in both basic and applied sciences, including therapeutic interventions. With advancements in recombinant protein technology, producing RPL41 for structural and functional studies has become feasible, further enhancing our knowledge of its role within the ribosomal context. Consequently, RPL41 serves as a valuable candidate for exploration to elucidate its contributions to normal cellular functions and disease mechanisms, paving the way for potential innovations in targeted therapies aimed at cancer and other ribosome-related disorders.
